rs6983561
|
|
Prostate carcinoma
|
|
0.780 |
GeneticVariation
|
BEFREE |
Therefore, this meta-analysis demonstrated that 8q24 polymorphisms (rs6983267 T>G, rs1447295 C>A, rs16901979 C>A, rs6983561 A>C and rs10090154 C>T) were associated with the susceptibility to PCa, which held the potential biomarkers for PCa risk.
|
29158792 |
2017 |
rs6983561
|
|
Prostate carcinoma
|
C |
0.780 |
GeneticVariation
|
GWASCAT |
A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.
|
26034056 |
2015 |
rs6983561
|
|
Prostate carcinoma
|
|
0.780 |
GeneticVariation
|
BEFREE |
Of the 82 known risk variants, 68 (83%) had effects that were directionally consistent in their association with prostate cancer risk and 30 (37%) were significantly associated with risk at p < 0.05, with the most statistically significant variants being rs116041037 (p = 3.7 × 10(-26) ) and rs6983561 (p = 1.1 × 10(-16) ) at 8q24, as well as rs7210100 (p = 5.4 × 10(-8) ) at 17q21.
|
25044450 |
2015 |
rs6983561
|
|
Prostate carcinoma
|
C |
0.780 |
GeneticVariation
|
GWASCAT |
Evaluating genetic risk for prostate cancer among Japanese and Latinos.
|
22923026 |
2012 |
rs6983561
|
|
Prostate carcinoma
|
|
0.780 |
GeneticVariation
|
BEFREE |
Early-onset marker rs6983561 adds potentially useful clinical information for African American men undergoing prostate cancer risk assessment.
|
22144497 |
2012 |
rs6983561
|
|
Prostate carcinoma
|
|
0.780 |
GeneticVariation
|
BEFREE |
In the Japanese population examined in this study, the rs6983561 polymorphism at 8q24 was significantly associated with prostate cancer mortality, especially among patients with metastatic disease.
|
21700508 |
2011 |
rs6983561
|
|
Prostate carcinoma
|
|
0.780 |
GeneticVariation
|
BEFREE |
Furthermore, the SNPs rs6983561 and rs4430796 were associated with a susceptibility to aggressive prostate cancer, whereas rs1859962 was associated with non-aggressive prostate cancer.
|
21557267 |
2011 |
rs6983561
|
|
Prostate carcinoma
|
|
0.780 |
GeneticVariation
|
BEFREE |
We found nominal evidence (P < 0.05) for association between prostate cancer and three chromosome 8q24 (rs6983561, rs16901979, and rs7000448) and two 10q11 (rs7904463 and rs10740051) SNPs.
|
20717903 |
2011 |
rs6983561
|
|
Prostate carcinoma
|
|
0.780 |
GeneticVariation
|
BEFREE |
The variants rs16901979 and rs6983561 at 8q24 are associated with prostate cancer risk in Taiwanese men.
|
19908238 |
2010 |
rs6983561
|
|
Prostate carcinoma
|
|
0.780 |
GeneticVariation
|
BEFREE |
Notably, rs6983561 was significantly associated with prostate cancer among men diagnosed at an early (<50 years) but not later age (p = 0.03 versus p = 0.21).
|
18360876 |
2008 |