Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.800 GeneticVariation UNIPROT Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the study of lung cancer/association for molecular pathology guideline. 25311215

2014
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.800 GeneticVariation UNIPROT Guideline Recommendations for Testing of ALK Gene Rearrangement in Lung Cancer: A Proposal of the Korean Cardiopulmonary Pathology Study Group. 24627688

2014
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.800 GeneticVariation UNIPROT Non-small cell lung cancer and precision medicine: a model for the incorporation of genomic features into clinical trial design. 24846033

2014
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.800 GeneticVariation UNIPROT Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. 23562183

2013
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.800 GeneticVariation UNIPROT Guideline Recommendations for EGFR Mutation Testing in Lung Cancer: Proposal of the Korean Cardiopulmonary Pathology Study Group. 23667368

2013
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		A 0.800 CausalMutation CLINVAR Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer. 23833300

2013
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		A 0.800 CausalMutation CLINVAR Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib. 22649091

2012
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		A 0.800 CausalMutation CLINVAR Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. 21483012

2011
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		A 0.800 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		A 0.800 CausalMutation CLINVAR Genetic predictors of MEK dependence in non-small cell lung cancer. 19010912

2008
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		A 0.800 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		A 0.800 CausalMutation CLINVAR Missense mutations of the BRAF gene in human lung adenocarcinoma. 12460919

2002
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		A 0.800 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002
dbSNP: rs121913351
rs121913351
BRAF
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.800 GeneticVariation UNIPROT Missense mutations of the BRAF gene in human lung adenocarcinoma. 12460919

2002