rs4488809
|
|
Carcinoma of lung
|
|
0.750 |
GeneticVariation
|
GWASCAT |
Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region.
|
31009812 |
2019 |
rs4488809
|
|
Carcinoma of lung
|
|
0.750 |
GeneticVariation
|
BEFREE |
The association between common variations (rs10937405, rs4488809) on 3q28 and lung cancer has been widely evaluated in various ethnic groups, since it was first identified through genome-wide association approach.
|
25344291 |
2015 |
rs4488809
|
|
Carcinoma of lung
|
|
0.750 |
GeneticVariation
|
BEFREE |
Our findings demonstrated that rs10937405-G allele and rs4488809-G allele might be risk-conferring factors for the development of lung cancer, especially for East Asian populations.
|
24466311 |
2014 |
rs4488809
|
|
Carcinoma of lung
|
|
0.750 |
GeneticVariation
|
BEFREE |
Four independent SNPs (rs2736100, rs402710, rs4488809 and rs4083914), were found to be associated with a risk of lung cancer.
|
23228068 |
2012 |
rs4488809
|
|
Carcinoma of lung
|
|
0.750 |
GeneticVariation
|
BEFREE |
To determine if this association with lung cancer risk is independent of tobacco use, we genotyped the TP63 SNPs reported by the previous GWAS (rs10937405 and rs4488809) in 3,467 never-smoking female lung cancer cases and 3,787 never-smoking female controls from 10 studies conducted in Taiwan, Mainland China, South Korea, and Singapore.
|
22367405 |
2012 |
rs4488809
|
|
Carcinoma of lung
|
C |
0.750 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.
|
23143601 |
2012 |
rs4488809
|
|
Carcinoma of lung
|
|
0.750 |
GeneticVariation
|
BEFREE |
The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).
|
21725308 |
2011 |
rs4488809
|
|
Carcinoma of lung
|
C |
0.750 |
GeneticVariation
|
GWASCAT |
The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).
|
21725308 |
2011 |