Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800796
rs1800796
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 GeneticVariation BEFREE The stratified analysis showed that rs1800796 G allele carriers (GG/CG) were associated with an increased risk of gastric cancer in the following subgroups: age >64 years old (OR<sub>adjusted</sub> = 1.67, 95% CI = 1.17-2.39), female (OR<sub>adjusted</sub> = 1.82, 95% CI = 1.09-3.05), positive for <i>H. pylori</i> infection (OR<sub>adjusted</sub> = 1.54, 95% CI = 1.07-2.22), non-cardiac gastric cancer (OR<sub>adjusted</sub> = 1.53, 95% CI = 1.15-2.04), stage T3-T4 tumor (OR<sub>adjusted</sub> = 1.41, 95% CI = 1.06-1.88), and gastric cancer with median to high differentiation (OR<sub>adjusted</sub> = 1.45, 95% CI = 1.08-1.96). 31312381

2019

dbSNP: rs1800796
rs1800796
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 GeneticVariation BEFREE Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer. 29552316

2018

dbSNP: rs1800796
rs1800796
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 GeneticVariation BEFREE Further subgroup analyses based on ethnicities of participants revealed that the IL-4 rs2243250, IL-6 rs1800796 and IL-8 rs4073 polymorphisms were significantly associated with the risk of GC in Asians. 30071135

2018

dbSNP: rs1800796
rs1800796
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 GeneticVariation BEFREE Epidemiological studies have evaluated the associations between interleukin-6 (IL-6) gene -174 C/G (rs1800795) and -572 C/G (rs1800796) polymorphisms and gastric cancer (GC) risk, but results and conclusions remain controversial. 22711691

2012