Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1049074086
rs1049074086
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 GeneticVariation BEFREE S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca(2+) ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas. 21947242

2012

dbSNP: rs1049074086
rs1049074086
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 GeneticVariation BEFREE The role of S100P in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D. 17875703

2007