Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE MTHFR C677T polymorphism was not associated with cervical cancer and HPV infection. 31170928

2019

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE Association of MTHFR 677C>T Polymorphism with Susceptibility to Ovarian and Cervical Cancers: A Systematic Review and Meta-Analysis. 31554347

2019

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE However, the MTHFR C677T polymorphism was not associated with the risk of cervical cancer or CIN. 29740106

2018

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE This study indicated that the MTHFR C677T may be no associated with cervical cancer risk, and yet the MTHFR A1298C polymorphism may be a risk factor for cervical cancer. 26879954

2016

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE Combination analysis of MTHFR C677T and A1298C polymorphisms revealed that combined MTHFR 677CC and 1298CC are strongly associated with a risk of cervical cancer. 27771518

2016

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE C677T polymorphism of MTHFR gene may increase the risk of cervical cancer in the complete over-dominant model. 23490201

2013

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE No effects of MTHFR C677T polymorphism on CIN II/III risk and MTHFR A1298C or MS A2756G polymorphisms on cervical cancer risk were detected. 23864153

2013

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE Association between Methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to cervical cancer: a meta-analysis. 23431363

2013

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE Cervical cancer with polymorphism in MTHFR C677T gene: a systematic review and meta-analysis. 23070908

2013

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE This meta-analysis supports an association between MTHFR 677C>T polymorphism and cervical cancer, and the effect of this association may be race specific. 23057736

2012

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE This meta-analysis suggests that White women with mutant C677T genotypes might have a lower risk of cervical cancer, yet lacking enough statistical robustness. 23029458

2012

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE The MTHFR C677T polymorphism is associated with cervical cancer risk in Asians, while any possible link in the Caucasian population needs further studies. 22901193

2012

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE In the present study, we have examined a large study population to determine whether the C677T polymorphism at the MTHFR locus affects susceptibility for cervical cancer or its precursor, cervical intraepithelial neoplasia (CIN). 15635481

2005

dbSNP: rs1217691063
rs1217691063
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.100 GeneticVariation BEFREE The effect of methylenetetrahydrofolate reductase polymorphism C677T on cervical cancer in Korean women. 15581963

2004