Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs25487
rs25487
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.090 GeneticVariation BEFREE We also observed that the rs25487 mutation was significantly increased within the cervical cancer</span> population. 30616520

2019

dbSNP: rs25487
rs25487
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.090 GeneticVariation BEFREE In view of the exiting heterogeneity, we did subgroup analysis stratified</span> by ethnicity, resulting in the fact that the Arg39</span>9Gln polymorphism was related to the decreased risk of cervical cancer. 27903984

2017

dbSNP: rs25487
rs25487
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.090 GeneticVariation BEFREE This meta-analysis showed that the XRCC1 Arg399Gln GA variant might be risk alleles for cervical cancer susceptibility in the Chinese population, and further studies in other ethnic groups are required to arrive at definite conclusions. 27487002

2017

dbSNP: rs25487
rs25487
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.090 GeneticVariation BEFREE This meta-analysis provides strongly statistical evidence for the association between rs1799782 and cervical cancer risk, as well as its association with rs25487 only in Asian populations. 24057881

2014

dbSNP: rs25487
rs25487
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.090 GeneticVariation BEFREE We found that the Arg194Trp polymorphism (Trp vs. Arg, OR=1.342, 95% CI: 1.176) was associated with increased risk of cervical cancer, while no significant association was found with Arg280His (His vs. Arg, OR=1.059, 95% CI: 0.863, 1.299) or Arg399Gln (Gln vs. Arg, OR=1.144, 95% CI: 0.938, 1.394). 23464469

2012

dbSNP: rs25487
rs25487
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.090 GeneticVariation BEFREE The XRCC1 Arg399Gln genetic variants were identified by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in patients with advanced cervical cancer (n=189) and controls (n=308). 21928248

2012

dbSNP: rs25487
rs25487
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.090 GeneticVariation BEFREE This meta-analysis suggests that Arg194Trp polymorphism may be associated with CC risk, Arg399Gln polymorphism might be a low-penetrent risk factor for CC only in Asians, and there may be no association between Arg280His polymorphism and CC risk. 22984511

2012

dbSNP: rs25487
rs25487
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.090 GeneticVariation BEFREE XRCC1 R399Q polymorphism is associated with response to platinum-based neoadjuvant chemotherapy in bulky cervical cancer. 16875718

2006

dbSNP: rs25487
rs25487
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.090 GeneticVariation BEFREE Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in Japanese subjects. 15990162

2005