Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs671
rs671
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Association of ADH1B Arg47His and ALDH2 Glu487Lys polymorphisms with risk of colorectal cancer and their interaction with environmental factors in a Chinese population. 27706775

2016

dbSNP: rs671
rs671
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Association between aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphism and susceptibility to colorectal cancer: a meta-analysis. 27706553

2016

dbSNP: rs671
rs671
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE A critical analysis of the relationship between aldehyde dehydrogenases-2 Glu487Lys polymorphism and colorectal cancer susceptibility. 25573590

2015

dbSNP: rs671
rs671
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Our results suggested that the ALDH2 Glu487Lys polymorphism may be associated with a decreased risk of colorectal cancer. 24558407

2014

dbSNP: rs671
rs671
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE In conclusion, the method based on crossover analysis-logistic regression is successful in assessing additive and multiplicative gene-environment interactions, and in revealing synergistic effects of gene loci rs671 and rs1329149 with alcohol consumption in the pathogenesis and development of colorectal cancer. 22901167

2012

dbSNP: rs671
rs671
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a southwestern Chinese population. 19706845

2009

dbSNP: rs671
rs671
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan. 16332725

2006

dbSNP: rs671
rs671
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE To examine associations between the risk of colorectal cancer and the CD36 gene A52C polymorphism according to the ALDH2 gene Glu487Lys polymorphism and drinking habit, a hospital-based case-control study was conducted with 128 colorectal cancer cases and 238 cancer-free controls. 15780035

2005