Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4938723
rs4938723
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.070 GeneticVariation BEFREE These findings indicate that the miR-34b/c rs4938723T > C polymorphism is an independent variable and associated with a decreased risk of CRC in Chinese population. 31349954

2019

dbSNP: rs4938723
rs4938723
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.070 GeneticVariation BEFREE CONCLUSIONS Current meta-analysis suggested that rs4938723 polymorphism was potentially associated with hepatocellular carcinoma risk, but this polymorphism had a decreased association for susceptibility to esophageal cancer, leukemia, and colorectal cancer. 30286050

2018

dbSNP: rs4938723
rs4938723
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.070 GeneticVariation BEFREE After stratifying by ethnicity and cancer type, genotype CT of rs4938723 was significantly association with an increased cancer risk in Asian population (P(h)=0.187, OR=1.10, 95%CI=1.01-1.20), allele C and genotype CT were significantly positive associated with hepatocellular cancer (P(h)=0.113, OR=1.11, 95%CI=1.01-1.23 for C vs. T; P(h)=0.121, OR=1.19, 95%CI=1.03-1.37 for CT vs. TT), but rs4938723 was negative associated with risk of colorectal cancer (P(h)=0.342, OR=0.66, 95%CI=0.47-0.92 for CC vs. TT; P(h)=0.519, OR=0.67, 95%CI=0.49-0.93 for CC vs. CT/TT; P(h)=0.443, OR=0.71, 95%CI=0.51-0.99 for CC/TT vs. CT). 25475831

2015

dbSNP: rs4938723
rs4938723
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.070 GeneticVariation BEFREE The current meta-analysis indicated that the miR-34b/c rs4938723 polymorphism may decrease susceptibility to colorectal cancer. 25227823

2014

dbSNP: rs4938723
rs4938723
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.070 GeneticVariation BEFREE The SNP rs4938723 and diabetes mellitus (DM) together were associated with an increased CRC risk, but the SNP TP53 Arg72Pro CC with DM showed a protective effect against CRC. 24337371

2014

dbSNP: rs4938723
rs4938723
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.070 GeneticVariation BEFREE This rs4938723 SNP showed an opposite tendency orientation between the hepatocellular cancer and colorectal cancer risks. 25201061

2014

dbSNP: rs4938723
rs4938723
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.070 GeneticVariation BEFREE These findings indicate that the rs4938723 in the promoter region of pri-miR-34b/c was a protective factor for the development of CRC. 23183747

2013