Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9929218
rs9929218
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.850 GeneticVariation BEFREE In summary, our analysis highlights significant association between rs9929218 polymorphism and CRC susceptibility. 27259261

2016

dbSNP: rs9929218
rs9929218
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.850 GeneticVariation BEFREE We demonstrate the potential of common inherited genetic variants to inform patient outcome and show that rs9929218 identifies approximately 8% of colorectal cancer patients with poor prognosis. rs9929218 may affect CDH1 expression and E-cadherin plays a role in epithelial-to-mesenchymal transition providing a mechanism underlying its prognostic potential. 25873087

2015

dbSNP: rs9929218
rs9929218
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.850 GeneticVariation BEFREE In conclusion, CRC susceptibility variants rs9929218 and rs10795668 may exert some influence in modulating patient's survival and they deserve to be further tested in additional CRC cohorts in order to confirm their potential as prognosis or predictive biomarkers. 23712746

2013

dbSNP: rs9929218
rs9929218
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.850 GeneticVariation BEFREE We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative interactions between each of the SNPs [rs16892766 at 8q23.3 (EIF3H/UTP23), rs6983267 at 8q24 (MYC), rs10795668 at 10p14 (FLJ3802842), rs3802842 at 11q23 (LOC120376), rs4444235 at 14q22.2 (BMP4), rs4779584 at 15q13 (GREM1), rs9929218 at 16q22.1 (CDH1), rs4939827 at 18q21 (SMAD7), rs10411210 at 19q13.1 (RHPN2), and rs961253 at 20p12.3 (BMP2)] and select major CRC risk factors (sex, body mass index, height, smoking status, aspirin/nonsteroidal anti-inflammatory drug use, alcohol use, and dietary intake of calcium, folate, red meat, processed meat, vegetables, fruit, and fiber). 22367214

2012

dbSNP: rs9929218
rs9929218
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.850 GeneticVariation BEFREE We also included rs4444235 and rs9929218, which did not fulfill our selection criteria but belonged to two genes in the BMP pathway and had consistently been linked to CRC in previous studies. 20844743

2010