Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799782
rs1799782
Childhood Acute Lymphoblastic Leukemia
0.060 GeneticVariation BEFREE Basal, H2O2-induced, and postrepair DNA damage; urinary 8-hydroxydeoxyguanosine level as a marker of oxidatively damaged DNA; and serum total antioxidant capacity were measured; XPD Lys751Gln, XRCC1 Arg399Gln, and XRCC1 Arg194Trp polymorphisms were analyzed in childhood acute lymphoblastic leukemia (ALL) survivors. 24577548

2015

dbSNP: rs1799782
rs1799782
Childhood Acute Lymphoblastic Leukemia
0.060 GeneticVariation BEFREE XRCC1 Arg399Gln and Arg194Trp polymorphisms in childhood acute lymphoblastic leukemia risk: a meta-analysis. 22712837

2013

dbSNP: rs1799782
rs1799782
Childhood Acute Lymphoblastic Leukemia
0.060 GeneticVariation BEFREE In this study, we investigated the possible association of X-ray repair cross-complimenting group 1 (XRCC1) Arg399Gln and Arg194Trp variants with the risk of incidence of childhood acute lymphoblastic leukemia (ALL) in Turkish population comprised of 190 healthy controls and 167 ALL patients. 20394984

2010

dbSNP: rs1799782
rs1799782
Childhood Acute Lymphoblastic Leukemia
0.060 GeneticVariation BEFREE We examined the influence of the Arg194Trp, Arg280His, and Arg399Gln polymorphisms of XRCC1 (X-ray repair cross-complementing group 1) on the development of childhood acute lymphoblastic leukemia (ALL) in 120 ALL patients and 120 controls in Mexico. 20013659

2009

dbSNP: rs1799782
rs1799782
Childhood Acute Lymphoblastic Leukemia
0.060 GeneticVariation BEFREE However, the combined XRCC1 Arg194Trp/Trp194Trp variant genotypes were associated with increased risk for ALL in females (OR=5.47; 95% CI=1.49-20.10; p=0.008). 19101034

2009

dbSNP: rs1799782
rs1799782
Childhood Acute Lymphoblastic Leukemia
0.060 GeneticVariation BEFREE We genotyped polymorphisms of X-ray repair cross-complimenting group 1 (XRCC1) codon 194 (Arg to Trp), 280 (Arg to His) and 399 (Arg to Gln), and xeroderma pigmentosum group D (XPD) codon 312 (Asp to Asn) and 715 (Lys to Gln) in 108 children with ALL and 317 healthy controls using PCR-RFLP method. 16435384

2007