Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799945
rs1799945
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.030 GeneticVariation BEFREE In the subgroup analysis, we illustrated the effect of the H63D polymorphism on hepatocellular carcinoma and pancreatic cancer risk, particularly in the Asian and African subgroups; however, this was not observed in gynecological malignant tumors. 26535689

2015

dbSNP: rs1799945
rs1799945
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.030 GeneticVariation BEFREE In addition, in the stratified analysis by cancer type, an increased risk was identified in hepatocellular carcinoma and breast cancer in C282Y polymorphism, as well as pancreatic cancer in H63D polymorphism, whereas a decreased risk of colorectal cancer was identified in C282Y polymorphism. 26107216

2015

dbSNP: rs1799945
rs1799945
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.030 GeneticVariation BEFREE Our observation that HFE rs1799945 increased PC risk warrants replication in additional study populations. 24798971

2014