Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs25489
rs25489
XRCC1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.030 GeneticVariation BEFREE Results from our stratified analysis based on Hardy-Weinberg equilibrium (HWE) showed that there was a robust significant association between Arg280His polymorphism and pancreatic cancer risk (allelic model, OR 0.743, 95% CI 0.576-0.958, P = 0.022; heterozygous model, OR 0.701, 95% CI 0.525-0.936, P = 0.016; dominant model, OR 0.710, 95% CI 0.537-0.939, P = 0.016). 29285737

2019
dbSNP: rs25489
rs25489
XRCC1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.030 GeneticVariation BEFREE In conclusion, we found that XRCC1 Arg399Gln genetic variations are associated with pancreatic cancer development, whereas the XRCC1 Arg280His and Arg194Trp polymorphisms did not affect pancreatic cancer risk. 27323136

2016
dbSNP: rs25489
rs25489
XRCC1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.030 GeneticVariation BEFREE A tendency of association between Arg280His and PC was also detected in the dominant model (OR, 0.70; 95% CI, 0.48-1.00). 26418909

2016