Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3212986
rs3212986
ERCC1 ; CD3EAP
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.040 GeneticVariation BEFREE The present meta-analysis showed significant associations between deoxyribonucleic acid (DNA) repair gene (X-ray repair cross-complementing group 1 (XRCC1) Arg399GIn and Arg194Trp, excision repair cross complementation 1 (ERCC1) rs11615 and rs3212986, ERCC2 rs13181) polymorphisms and PC risk. 31393355

2019
dbSNP: rs3212986
rs3212986
ERCC1 ; CD3EAP
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.040 GeneticVariation BEFREE Unconditional logistic regression analyses showed that subjects with the CC genotype of ERCC1 rs3212986 were susceptible to the development of pancreatic cancer when compared with subjects with the AA genotype (OR = 2.57, 95%CI = 1.34-5.02). 27051038

2016
dbSNP: rs3212986
rs3212986
ERCC1 ; CD3EAP
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.040 GeneticVariation BEFREE In summary, we found that the presence of the ERCC1 rs3212986 polymorphism correlated with an increased risk of pancreatic cancer. 27050953

2016
dbSNP: rs3212986
rs3212986
ERCC1 ; CD3EAP
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.040 GeneticVariation BEFREE We found that individuals carrying with GT+TT genotype of ERCC1 rs3212986 and TG+GG genotype of ERCC2 rs1318 gene polymorphisms were correlated with higher risk of pancreatic cancer in smokers when compared with non-smokers, and the adjusted ORs (95% CI) were 1.89 (1.05-3.40) and 1.88 (1.06-3.34), respectively. 26617894

2015