Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6983561
rs6983561
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.780 GeneticVariation BEFREE Therefore, this meta-analysis demonstrated that 8q24 polymorphisms (rs6983267 T>G, rs1447295 C>A, rs16901979 C>A, rs6983561 A>C and rs10090154 C>T) were associated with the susceptibility to PCa, which held the potential biomarkers for PCa risk. 29158792

2017

dbSNP: rs6983561
rs6983561
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.780 GeneticVariation BEFREE Of the 82 known risk variants, 68 (83%) had effects that were directionally consistent in their association with prostate cancer risk and 30 (37%) were significantly associated with risk at p < 0.05, with the most statistically significant variants being rs116041037 (p = 3.7 × 10(-26) ) and rs6983561 (p = 1.1 × 10(-16) ) at 8q24, as well as rs7210100 (p = 5.4 × 10(-8) ) at 17q21. 25044450

2015

dbSNP: rs6983561
rs6983561
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.780 GeneticVariation BEFREE Early-onset marker rs6983561 adds potentially useful clinical information for African American men undergoing prostate cancer risk assessment. 22144497

2012

dbSNP: rs6983561
rs6983561
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.780 GeneticVariation BEFREE Furthermore, the SNPs rs6983561 and rs4430796 were associated with a susceptibility to aggressive prostate cancer, whereas rs1859962 was associated with non-aggressive prostate cancer. 21557267

2011

dbSNP: rs6983561
rs6983561
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.780 GeneticVariation BEFREE We found nominal evidence (P < 0.05) for association between prostate cancer and three chromosome 8q24 (rs6983561, rs16901979, and rs7000448) and two 10q11 (rs7904463 and rs10740051) SNPs. 20717903

2011

dbSNP: rs6983561
rs6983561
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.780 GeneticVariation BEFREE In the Japanese population examined in this study, the rs6983561 polymorphism at 8q24 was significantly associated with prostate cancer mortality, especially among patients with metastatic disease. 21700508

2011

dbSNP: rs6983561
rs6983561
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.780 GeneticVariation BEFREE The variants rs16901979 and rs6983561 at 8q24 are associated with prostate cancer risk in Taiwanese men. 19908238

2010

dbSNP: rs6983561
rs6983561
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.780 GeneticVariation BEFREE Notably, rs6983561 was significantly associated with prostate cancer among men diagnosed at an early (<50 years) but not later age (p = 0.03 versus p = 0.21). 18360876

2008