Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121434568
rs121434568
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.030 GeneticVariation BEFREE Therefore, EGFR L858R mutation and exon 19 deletion may not be identical disease entity from the point of carcinogenesis. 26645716

2016

dbSNP: rs121434568
rs121434568
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.030 GeneticVariation BEFREE These results identify a novel link between the p14(ARF) and EGFR pathways and suggest that EGFR L858R counteracts the pro-apoptotic function of p14(ARF) by downregulating its expression to promote carcinogenesis. 22450744

2013

dbSNP: rs121434568
rs121434568
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.030 GeneticVariation BEFREE Genetic analysis suggested that the specific EGFR mutation L858R in exon 21 might be the main factor contributing to lung carcinogenesis in multiple lung cancers. 22733594

2012