Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE The purpose of this study was to examine the role of the miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms in the susceptibility of gastric cancer. 25658980

2015

dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE We found that the polymorphisms of P53 (rs1042522) and MDM2 (rs2279744) are associated with gastric cancer risk, whereas no significant association was observed between variant genotype of other two polymorphisms (MDM4 rs1380576 and Hausp rs1529916) and gastric cancer risk. 25479941

2015

dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE The purpose of the present hospital-based case-control study was to investigate the association between the miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms and the risk of gastric cancer. 25190020

2014

dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE The p53 R72P seems not to be a potential risk factor for development of GC among Iranian patients, but our data suggest that MDM2 SNP309 might modify the risk related to GC. 25227851

2014

dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE These results suggest that TP53 rs1042522 polymorphism might contribute to the susceptibility of gastric cancer under the dominant model, especially in Eastern Asians. 24534481

2014

dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE This meta-analysis suggests that p53 Arg72Pro polymorphism is associated with increased risk of gastric cancer in Asians. 22780299

2012

dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE This meta-analysis suggests the Pro variant of TP53 Arg72Pro contributes to gastric cancer risk in Asians. 22631671

2012

dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE Overall, a significant association was detected between the p53 Arg72Pro polymorphism and GC risk (Pro-allele vs. Arg-allele: OR=1.05, 95%CI=1.01-1.08; Pro/Pro vs. Arg/Arg: OR=1.13, 95%CI=1.04-1.22). 22901123

2012

dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE This meta-analysis suggests that Pro allele in P53 Arg72Pro is significantly associated with the increased risks of digestive tract cancers, especially for Asians, and for gastric cancer, colorectal cancer and gallbladder and pancreatic cancer. 21376265

2011

dbSNP: rs1042522
rs1042522
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 GeneticVariation BEFREE Aiming to evaluate the associations between host cell proliferation-related genetic polymorphisms and gastric cancer susceptibility, we reviewed the related studies published until 15 September 2008 and quantitatively summarized the associations of the most widely studied polymorphisms (TP53 Arg72Pro, L-myc EcoRI) using meta-analysis. 19536170

2009