Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799782
rs1799782
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Related databases of Medline, CNKI, and Wanfang were systematic searched for the studies related to XRCC1 rs1799782 C>T polymorphisms and colorectal cancer risk in Chinese Han population. 28230032

2016

dbSNP: rs1799782
rs1799782
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Our results suggest an increased risk for CRC in individuals with XRCC1 Arg194Trp polymorphism suggesting BER repair pathway modulates the risk of developing colorectal cancer in the Kashmiri population. 26434847

2015

dbSNP: rs1799782
rs1799782
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Association between X-ray repair cross-complementing group 1 Arg194Trp polymorphism and colorectal cancer risk. 23857281

2013

dbSNP: rs1799782
rs1799782
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Therefore, we examined the associations of XRCC1 Arg399Gln, Arg280His, and Arg194Trp polymorphisms with colorectal cancer and the impact of the association between alcohol consumption and colorectal cancer risk. 22186158

2012

dbSNP: rs1799782
rs1799782
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal cancer risk. 21612998

2011

dbSNP: rs1799782
rs1799782
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE The purpose of this study is to evaluate the role of XRCC1 R399Q, R194W, and XRCC3 T241M genotypes in colorectal cancer susceptibility. 19915856

2010

dbSNP: rs1799782
rs1799782
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE No association is found between the polymorphisms in XRCC1 (Arg399Gln, Arg280His, and Arg194Trp) and risk of colorectal cancer. 20033188

2010

dbSNP: rs1799782
rs1799782
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Our results showed no evidence of a relationship between the XRCC1 Arg194Trp and Arg399Gln polymorphisms and the risk of lung and colorectal cancer. 19031937

2009