Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer. 29394274

2018

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Association between the XRCC3 Thr241Met polymorphism and risk of colorectal cancer: a meta analysis of 5,193 cases and 6,645 controls. 25824748

2015

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Meta-analysis of the relationship between XRCC3 T241M polymorphism and colorectal cancer susceptibility. 26600544

2015

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE No association between XRCC3 Thr241Met and XPD Lys751Gln polymorphisms and the risk of colorectal cancer in West Algerian population: a case-control study. 24687779

2014

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE XRCC3 Thr241Met gene polymorphism and risk of colorectal cancer in Kashmir: a case control study. 25520078

2014

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Association between XRCC3 Thr241Met polymorphism and colorectal cancer risk. 23504553

2013

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE The Thr241Met polymorphism of the XRCC3 gene and the Arg188His polymorphism of the XRCC2 gene can modify the risk of colorectal cancer. 21104022

2011

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE The purpose of this study is to evaluate the role of XRCC1 R399Q, R194W, and XRCC3 T241M genotypes in colorectal cancer susceptibility. 19915856

2010

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE This study was designed to examine the polymorphisms associated with two DNA repair genes, namely XRCC1 Arg194Trp, XRCC1 Arg399Gln and XRCC3 Thr241Met, and to investigate their role as susceptibility markers for lung and colorectal cancer. 19031937

2009

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorectal cancer in a Chinese population. 16271954

2005

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE This study was designed to examine the polymorphisms associated with three DNA repair genes, namely: XRCC1 Arg399Gln, XRCC3 Thr241Met and XPD Lys751Gln, and investigate their role as susceptibility markers for colorectal cancer. 15679883

2005

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the risk of early-onset colorectal cancer and the XRCC3 Thr241Met polymorphism may modify the risk for meat-associated colorectal cancer. 15914278

2005

dbSNP: rs861539
rs861539
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE We performed a case-control study (51 cases and 100 controls) to test the association between two polymorphisms: Arg399Gln in the XRCC1 gene and Thr241Met in the XRCC3 gene and colorectal cancer risk. 15354414

2004