Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
C 0.700 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
C 0.700 CausalMutation CLINVAR PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers. 21829508

2011

dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
C 0.700 CausalMutation CLINVAR Development of molecular biomarkers in individualized treatment of colorectal cancer. 21729679

2011

dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
C 0.700 CausalMutation CLINVAR Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer. 21305640

2011

dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
C 0.700 CausalMutation CLINVAR NRAS mutations are rare in colorectal cancer. 20736745

2010

dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
C 0.700 CausalMutation CLINVAR Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. 20619739

2010

dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
C 0.700 CausalMutation CLINVAR AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models. 17699718

2007

dbSNP: rs11554290
rs11554290
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
C 0.700 CausalMutation CLINVAR BRAF mutation predicts sensitivity to MEK inhibition. 16273091

2006

dbSNP: rs121434595
rs121434595
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121434596
rs121434596
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121434596
rs121434596
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
G 0.700 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
T 0.700 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
A 0.700 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
G 0.700 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
A 0.700 CausalMutation CLINVAR PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers. 21829508

2011

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
G 0.700 CausalMutation CLINVAR Development of molecular biomarkers in individualized treatment of colorectal cancer. 21729679

2011

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
T 0.700 CausalMutation CLINVAR PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers. 21829508

2011

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
T 0.700 CausalMutation CLINVAR Development of molecular biomarkers in individualized treatment of colorectal cancer. 21729679

2011

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
A 0.700 CausalMutation CLINVAR Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer. 21305640

2011

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
T 0.700 CausalMutation CLINVAR Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer. 21305640

2011

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
G 0.700 CausalMutation CLINVAR Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer. 21305640

2011

dbSNP: rs121913237
rs121913237
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
A 0.700 CausalMutation CLINVAR Development of molecular biomarkers in individualized treatment of colorectal cancer. 21729679

2011