Source: CLINVAR

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs104894230
rs104894230
HRAS ; LRRC56
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs104894230
rs104894230
HRAS ; LRRC56
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		A 0.700 CausalMutation CLINVAR Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer. 23406027

2013
dbSNP: rs104894230
rs104894230
HRAS ; LRRC56
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		A 0.700 CausalMutation CLINVAR Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma. 19773371

2009
dbSNP: rs104894230
rs104894230
HRAS ; LRRC56
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		A 0.700 CausalMutation CLINVAR Phase II trial of sorafenib in metastatic thyroid cancer. 19255327

2009
dbSNP: rs104894230
rs104894230
HRAS ; LRRC56
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		A 0.700 CausalMutation CLINVAR Hyperactive Ras in developmental disorders and cancer. 17384584

2007