Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.400 None 0.800 148 7 1990 2019
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
P05091 aldehyde dehydrogenase 2 family member Enzyme 337 0.457 0.885 3.4E-10 0.700 None 1.000 137 4 1991 2019
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 224 0.502 0.846 9.9E-07 0.700 None 1.000 114 16 1994 2019
Entrez Id: 10327
Gene Symbol: AKR1A1
AKR1A1
P14550 aldo-keto reductase family 1 member A1 Enzyme 185 0.510 0.846 6.7E-07 0.400 None 1.000 58 0 1977 2019
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.600 None 0.800 56 2 1998 2019
Entrez Id: 126
Gene Symbol: ADH1C
ADH1C
P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide Enzyme 146 0.547 0.731 0.700 None 1.000 55 10 1991 2019
Entrez Id: 551
Gene Symbol: AVP
AVP
P01185 arginine vasopressin Signaling 454 0.437 0.846 7.4E-02 0.100 None 0.962 53 0 1988 2019
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
P31645 solute carrier family 6 member 4 Transporter 440 0.429 0.808 0.25 0.600 None 0.800 53 4 1998 2020
Entrez Id: 2555
Gene Symbol: GABRA2
GABRA2
P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 60 0.641 0.346 1.00 0.700 None 0.800 51 4 2004 2017
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.400 None 1.000 29 2 1995 2019
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.400 None 0.800 28 0 1989 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.400 None 0.400 26 4 2004 2020
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
P21397 monoamine oxidase A 300 0.465 0.769 1.00 0.400 None 1.000 25 1 1995 2018
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.400 None 0.875 24 4 1999 2018
Entrez Id: 255239
Gene Symbol: ANKK1
ANKK1
Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 71 0.604 0.462 7.4E-12 0.400 None 0.800 22 1 2004 2017
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
P05181 cytochrome P450 family 2 subfamily E member 1 306 0.459 0.885 8.1E-09 0.600 None 1.000 22 0 1995 2018
Entrez Id: 4852
Gene Symbol: NPY
NPY
P01303 neuropeptide Y Signaling 381 0.447 0.846 0.14 0.600 None 1.000 19 1 2001 2017
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B
P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 140 0.551 0.769 0.19 0.400 None 1.000 18 4 1998 2019
Entrez Id: 127
Gene Symbol: ADH4
ADH4
P08319 alcohol dehydrogenase 4 (class II), pi polypeptide Enzyme 53 0.641 0.462 8.1E-07 0.500 None 1.000 16 8 1994 2019
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
P21917 dopamine receptor D4 G-protein coupled receptor 189 0.517 0.577 9.3E-09 0.400 None 1.000 16 0 1995 2015
Entrez Id: 5173
Gene Symbol: PDYN
PDYN
P01213 prodynorphin Signaling 197 0.535 0.577 1.7E-04 0.600 None 0.800 14 3 1997 2018
Entrez Id: 1814
Gene Symbol: DRD3
DRD3
P35462 dopamine receptor D3 G-protein coupled receptor 199 0.529 0.692 2.4E-03 0.400 None 0.800 14 2 1995 2018
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1
P41145 opioid receptor kappa 1 G-protein coupled receptor 156 0.555 0.615 4.1E-05 0.400 None 0.800 12 0 2004 2018
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
P34998 corticotropin releasing hormone receptor 1 183 0.517 0.769 3.8E-05 0.400 None 1.000 12 3 2005 2015
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 289 0.473 0.846 0.51 0.700 None 1.000 12 1 1999 2014