Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.500 None 0.941 34 4 1992 2018
Entrez Id: 55806
Gene Symbol: HR
HR
O43593 HR lysine demethylase and nuclear receptor corepressor Transcription factor 29 0.722 0.192 7.4E-10 0.430 None 1.000 4 0 2002 2012
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
P31213 steroid 5 alpha-reductase 2 Enzyme 106 0.564 0.615 0.430 None 0.500 4 2 2003 2017
Entrez Id: 4047
Gene Symbol: LSS
LSS
P48449 lanosterol synthase 74 0.606 0.654 1.8E-07 0.420 moderate 1.000 3 0 2017 2019
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1
Q92743 HtrA serine peptidase 1 Enzyme 164 0.532 0.692 4.9E-04 0.410 strong 1.000 2 0 2011 2015
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 427 0.426 0.885 0.99 0.400 strong 1.000 1 0 2010 2010
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.390 None 1.000 10 2 2000 2016
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.320 None 1.000 2 1 2008 2013
Entrez Id: 54503
Gene Symbol: ZDHHC13
ZDHHC13
Q8IUH4 zinc finger DHHC-type palmitoyltransferase 13 18 0.729 0.346 1.2E-19 0.310 None 1.000 2 0 2010 2014
Entrez Id: 1392
Gene Symbol: CRH
CRH
P06850 corticotropin releasing hormone Signaling 402 0.439 0.808 0.72 0.310 None 1.000 2 0 2001 2011
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
Q92887 ATP binding cassette subfamily C member 2 Transporter 254 0.483 0.808 5.2E-47 0.310 None 1.000 1 1 2008 2008
Entrez Id: 4953
Gene Symbol: ODC1
ODC1
P11926 ornithine decarboxylase 1 Enzyme 184 0.510 0.731 0.17 0.300 strong 1.000 1 0 2018 2018
Entrez Id: 6832
Gene Symbol: SUPV3L1
SUPV3L1
Q8IYB8 Suv3 like RNA helicase 13 0.821 0.115 3.2E-02 0.300 None 1.000 1 0 2009 2009
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 597 0.401 0.846 1.00 0.300 None 1.000 1 0 2018 2018
Entrez Id: 7538
Gene Symbol: ZFP36
ZFP36
P26651 ZFP36 ring finger protein Nucleic acid binding 161 0.523 0.692 0.75 0.300 None 1.000 1 0 2005 2005
Entrez Id: 387
Gene Symbol: RHOA
RHOA
P61586 ras homolog family member A Enzyme modulator 193 0.502 0.808 0.60 0.300 None 1.000 1 0 2019 2019
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A
O00220 TNF receptor superfamily member 10a 155 0.521 0.731 5.1E-15 0.300 None 1.000 1 0 2009 2009
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
O60885 bromodomain containing 4 Epigenetic regulator 335 0.446 0.885 1.00 0.300 None 1.000 1 0 2014 2014
Entrez Id: 142
Gene Symbol: PARP1
PARP1
P09874 poly(ADP-ribose) polymerase 1 565 0.389 0.923 3.3E-04 0.300 None 1.000 1 0 2010 2010
Entrez Id: 55711
Gene Symbol: FAR2
FAR2
Q96K12 fatty acyl-CoA reductase 2 13 0.805 0.308 0.56 0.210 None 1.000 1 0 2018 2018
Entrez Id: 326
Gene Symbol: AIRE
AIRE
O43918 autoimmune regulator 175 0.516 0.808 4.0E-12 0.180 None 1.000 8 2 2002 2020
Entrez Id: 55270
Gene Symbol: NUDT15
NUDT15
Q9NV35 nudix hydrolase 15 33 0.670 0.538 1.7E-03 0.160 None 1.000 6 1 2016 2018
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.160 None 1.000 6 0 2002 2018
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha Receptor 540 0.389 0.885 5.5E-02 0.150 None 0.800 5 0 2012 2019
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 400 0.438 0.846 3.5E-21 0.150 None 1.000 5 1 2006 2019