Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.400 None 0.955 132 0 1995 2020
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.100 None 0.938 65 0 1990 2020
Entrez Id: 335
Gene Symbol: APOA1
APOA1 		P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.100 None 0.950 40 1 1998 2019
Entrez Id: 4210
Gene Symbol: MEFV
MEFV 		O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.100 None 0.941 34 6 1998 2019
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		F7VJQ1 P04156 prion protein 426 0.445 0.923 6.3E-04 0.100 None 0.941 34 1 1993 2019
Entrez Id: 4069
Gene Symbol: LYZ
LYZ 		P61626 lysozyme 178 0.526 0.846 3.4E-06 0.100 None 1.000 24 5 1988 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 19 0 2006 2019
Entrez Id: 1471
Gene Symbol: CST3
CST3 		P01034 cystatin C 370 0.436 0.808 3.9E-03 0.100 None 0.929 14 1 1989 2017
Entrez Id: 54209
Gene Symbol: TREM2
TREM2 		Q9NZC2 triggering receptor expressed on myeloid cells 2 239 0.519 0.769 3.3E-09 0.100 None 1.000 12 0 2010 2019
Entrez Id: 325
Gene Symbol: APCS
APCS 		P02743 amyloid P component, serum 141 0.531 0.808 3.2E-02 0.100 None 1.000 11 1 1987 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 0.909 11 0 2006 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 10 0 1993 2020
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		P14136 glial fibrillary acidic protein 447 0.421 0.885 1.5E-06 0.100 None 1.000 10 0 2017 2019
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		P06276 butyrylcholinesterase 392 0.447 0.923 1.1E-13 0.100 None 1.000 10 0 2005 2020
Entrez Id: 1191
Gene Symbol: CLU
CLU 		P10909 clusterin 412 0.426 0.885 7.8E-05 0.090 None 1.000 9 3 2009 2018
Entrez Id: 4747
Gene Symbol: NEFL
NEFL 		P07196 neurofilament light 247 0.488 0.769 0.090 None 1.000 9 0 2017 2019
Entrez Id: 102
Gene Symbol: ADAM10
ADAM10 		O14672 ADAM metallopeptidase domain 10 224 0.489 0.846 1.00 0.080 None 1.000 8 0 2011 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.080 None 1.000 8 0 2006 2019
Entrez Id: 3565
Gene Symbol: IL4
IL4 		P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.070 None 1.000 7 0 2008 2019
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.060 None 1.000 6 0 2013 2019
Entrez Id: 274
Gene Symbol: BIN1
BIN1 		O00499 bridging integrator 1 163 0.550 0.692 0.78 0.060 None 0.667 6 0 2013 2019
Entrez Id: 4900
Gene Symbol: NRGN
NRGN 		Q92686 neurogranin 69 0.608 0.615 0.48 0.060 None 0.833 6 0 2017 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.060 None 1.000 6 0 2007 2018
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1 		P36222 chitinase 3 like 1 420 0.419 0.885 1.1E-05 0.050 None 1.000 5 0 2017 2019
Entrez Id: 4035
Gene Symbol: LRP1
LRP1 		Q07954 LDL receptor related protein 1 252 0.482 0.769 1.00 0.050 None 1.000 5 0 2011 2019