Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.800 strong 0.985 1565 24 1993 2020
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72
Q96LT7 C9orf72-SMCR8 complex subunit 258 0.496 0.769 1.1E-06 0.800 limited 0.985 520 15 2009 2020
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.700 None 0.979 721 18 2006 2020
Entrez Id: 2521
Gene Symbol: FUS
FUS
P35637 FUS RNA binding protein Nucleic acid binding 301 0.470 0.846 1.00 0.700 None 0.981 310 16 2009 2020
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2
Q99700 ataxin 2 Nucleic acid binding 341 0.482 0.808 0.85 0.700 None 0.971 68 4 2006 2019
Entrez Id: 10133
Gene Symbol: OPTN
OPTN
Q96CV9 optineurin 136 0.548 0.808 5.9E-18 0.700 None 0.954 65 8 2010 2020
Entrez Id: 29110
Gene Symbol: TBK1
TBK1
Q9UHD2 TANK binding kinase 1 Kinase 207 0.513 0.846 7.5E-02 0.700 strong 1.000 41 3 2015 2019
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Q13501 sequestosome 1 470 0.428 0.885 8.6E-04 0.700 None 0.974 38 4 2009 2020
Entrez Id: 9782
Gene Symbol: MATR3
MATR3
P43243 matrin 3 92 0.631 0.538 1.00 0.700 limited 1.000 21 2 2009 2019
Entrez Id: 23025
Gene Symbol: UNC13A
UNC13A
Q9UPW8 unc-13 homolog A 41 0.705 0.423 1.00 0.700 None 1.000 17 3 2009 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.700 None 0.929 14 3 2007 2019
Entrez Id: 8148
Gene Symbol: TAF15
TAF15
Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 74 0.626 0.500 0.17 0.700 limited 0.929 14 0 2011 2019
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B
Q9UQN3 charged multivesicular body protein 2B 177 0.543 0.731 4.6E-06 0.680 None 1.000 10 0 2006 2016
Entrez Id: 4750
Gene Symbol: NEK1
NEK1
Q96PY6 NIMA related kinase 1 Kinase 131 0.575 0.769 1.9E-25 0.680 None 1.000 9 2 2016 2019
Entrez Id: 1610
Gene Symbol: DAO
DAO
P14920 D-amino acid oxidase 78 0.636 0.615 6.2E-22 0.670 moderate 1.000 9 1 2010 2018
Entrez Id: 755
Gene Symbol: CFAP410
CFAP410
O43822 cilia and flagella associated protein 410 73 0.633 0.615 3.3E-07 0.620 None 1.000 4 1 2016 2019
Entrez Id: 7415
Gene Symbol: VCP
VCP
P55072 valosin containing protein 376 0.469 0.923 1.00 0.500 None 0.962 52 8 2008 2020
Entrez Id: 283
Gene Symbol: ANG
ANG
P03950 angiogenin 185 0.511 0.769 0.29 0.500 None 0.959 49 7 2004 2019
Entrez Id: 29978
Gene Symbol: UBQLN2
UBQLN2
Q9UHD9 ubiquilin 2 59 0.656 0.462 0.85 0.500 None 0.980 49 9 2011 2020
Entrez Id: 5216
Gene Symbol: PFN1
PFN1
P07737 profilin 1 119 0.565 0.769 0.73 0.500 None 1.000 36 5 2012 2019
Entrez Id: 9217
Gene Symbol: VAPB
VAPB
O95292 VAMP associated protein B and C Transporter 55 0.666 0.423 0.58 0.500 None 0.967 30 3 2004 2019
Entrez Id: 400916
Gene Symbol: CHCHD10
CHCHD10
Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 112 0.623 0.462 5.4E-06 0.500 None 0.955 22 3 2014 2020
Entrez Id: 23064
Gene Symbol: SETX
SETX
Q7Z333 senataxin Enzyme 133 0.570 0.731 0.95 0.500 moderate 0.952 21 3 1998 2018
Entrez Id: 4744
Gene Symbol: NEFH
NEFH
P12036 neurofilament heavy 120 0.588 0.769 2.7E-12 0.500 None 1.000 20 1 1993 2018
Entrez Id: 3178
Gene Symbol: HNRNPA1
HNRNPA1
P09651 heterogeneous nuclear ribonucleoprotein A1 188 0.529 0.885 1.00 0.500 None 1.000 18 2 2013 2019