Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 55066
Gene Symbol: PDPR
PDPR 		Q8NCN5 pyruvate dehydrogenase phosphatase regulatory subunit Enzyme 1 9.4E-09 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.050 None 1.000 5 0 2017 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.050 None 1.000 5 0 2013 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.020 None 1.000 2 0 2018 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.020 None 1.000 2 0 2017 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.150 None 1.000 5 0 2017 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1410 0.299 0.962 3.7E-03 0.050 None 1.000 5 0 2013 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.010 None 1.000 1 0 2009 2009
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.010 None 1.000 1 0 2019 2019
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 1089 0.317 0.962 0.64 0.020 None 1.000 2 0 2017 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1105 0.319 0.885 1.00 0.040 None 1.000 4 0 2017 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.040 None 1.000 4 0 2017 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.040 None 1.000 4 0 2017 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1029 0.322 0.923 4.5E-04 0.020 None 1.000 2 0 2018 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1034 0.324 0.923 4.3E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 979 0.328 0.923 1.0E-37 0.380 None 1.000 7 0 2004 2019
Entrez Id: 3565
Gene Symbol: IL4
IL4 		P05112 interleukin 4 926 0.332 0.962 4.7E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 839 0.333 0.923 1.1E-03 0.010 None 1.000 1 0 1998 1998
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 839 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 2006 2006
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 807 0.349 0.846 0.46 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5443
Gene Symbol: POMC
POMC 		P01189 proopiomelanocortin 665 0.356 0.846 1.2E-04 0.010 None 1.000 1 0 2005 2005
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 717 0.357 0.923 8.5E-17 0.010 None < 0.001 1 0 2005 2005