Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.700 None 0.975 1014 8 1989 2020
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 400 0.438 0.846 3.5E-21 0.700 None 0.899 158 7 2004 2019
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
Q9H015 solute carrier family 22 member 4 Transporter 90 0.603 0.769 1.8E-08 0.700 None 0.857 21 3 2003 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.600 None 0.955 199 1 1989 2020
Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST
P40189 interleukin 6 signal transducer Signaling 260 0.475 0.808 1.00 0.590 None 0.909 11 1 2000 2020
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.500 None 0.936 575 7 1989 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.500 None 0.946 129 3 1994 2020
Entrez Id: 23569
Gene Symbol: PADI4
PADI4
Q9UM07 peptidyl arginine deiminase 4 196 0.494 0.808 4.6E-16 0.500 None 0.912 125 10 2003 2020
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 316 0.471 0.769 0.77 0.500 None 0.889 63 9 2000 2019
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
Q13077 TNF receptor associated factor 1 Signaling 119 0.554 0.731 3.6E-03 0.500 None 0.850 40 3 2007 2019
Entrez Id: 940
Gene Symbol: CD28
CD28
P10747 CD28 molecule 364 0.436 0.885 0.36 0.500 None 1.000 36 2 1996 2018
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
P21580 TNF alpha induced protein 3 Enzyme 212 0.481 0.808 1.00 0.500 None 1.000 35 8 2007 2018
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
P08887 interleukin 6 receptor Signaling 261 0.471 0.846 3.2E-05 0.500 None 0.971 34 5 2001 2019
Entrez Id: 958
Gene Symbol: CD40
CD40
P25942 CD40 molecule 528 0.396 0.846 0.85 0.500 None 0.848 33 5 2002 2019
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
P04440 major histocompatibility complex, class II, DP beta 1 Immune response 324 0.453 0.923 5.3E-10 0.500 None 0.938 32 62 1988 2020
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha Receptor 540 0.389 0.885 5.5E-02 0.500 None 1.000 32 3 1992 2019
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
Q13568 interferon regulatory factor 5 Transcription factor 226 0.489 0.731 9.0E-03 0.500 None 0.906 32 6 2006 2019
Entrez Id: 1235
Gene Symbol: CCR6
CCR6
P51684 C-C motif chemokine receptor 6 G-protein coupled receptor 231 0.485 0.808 5.8E-03 0.500 None 1.000 27 8 2001 2019
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A
P12318 Fc fragment of IgG receptor IIa Cell adhesion 227 0.480 0.769 2.0E-06 0.500 None 0.852 27 3 2002 2020
Entrez Id: 4261
Gene Symbol: CIITA
CIITA
P33076 class II major histocompatibility complex transactivator 149 0.536 0.808 1.4E-07 0.500 None 0.533 15 3 2006 2017
Entrez Id: 7189
Gene Symbol: TRAF6
TRAF6
Q9Y4K3 TNF receptor associated factor 6 Signaling 254 0.472 0.808 1.00 0.500 None 1.000 13 1 2008 2019
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
P29597 tyrosine kinase 2 Kinase 172 0.505 0.769 4.5E-08 0.490 None 1.000 15 3 2007 2019
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.490 None 0.786 14 4 2003 2019
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
P17706 protein tyrosine phosphatase non-receptor type 2 134 0.538 0.692 1.00 0.490 None 1.000 13 4 2012 2019
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
P08575 protein tyrosine phosphatase receptor type C Enzyme 366 0.435 0.808 1.00 0.480 None 1.000 10 1 1991 2017