Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 1.000 None 0.982 623 680 1953 2020
Entrez Id: 160140
Gene Symbol: C11orf65
C11orf65 		Q8NCR3 chromosome 11 open reading frame 65 45 0.670 0.462 2.0E-14 0.100 None 1.000 180 265 1953 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.040 None 1.000 4 2 2017 2019
Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2 		O15244 solute carrier family 22 member 2 Transporter 98 0.572 0.769 2.0E-12 0.010 None 1.000 1 2 2011 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.939 49 1 1992 2019
Entrez Id: 23064
Gene Symbol: SETX
SETX 		Q7Z333 senataxin Enzyme 133 0.570 0.731 0.95 0.080 None 0.875 8 1 2004 2018
Entrez Id: 6916
Gene Symbol: TBXAS1
TBXAS1 		P24557 thromboxane A synthase 1 77 0.619 0.615 1.4E-20 0.010 None 1.000 1 1 2011 2011
Entrez Id: 256130
Gene Symbol: TMEM196
TMEM196 		Q5HYL7 transmembrane protein 196 13 0.839 0.269 4.2E-06 0.010 None 1.000 1 1 2019 2019
Entrez Id: 2176
Gene Symbol: FANCC
FANCC 		Q00597 FA complementation group C 218 0.507 0.808 2.8E-13 0.010 None 1.000 1 1 2012 2012
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None 1.000 1 1 2009 2009
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.010 None 1.000 1 1 2005 2005
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		P07550 adrenoceptor beta 2 G-protein coupled receptor 387 0.442 0.923 0.53 0.010 None 1.000 1 1 2011 2011
Entrez Id: 174
Gene Symbol: AFP
AFP 		P02771 alpha fetoprotein Transporter 392 0.429 0.885 1.1E-11 0.100 None 0.944 18 0 1980 2019
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		P16104 H2A.X variant histone Nucleic acid binding 212 0.484 0.808 0.18 0.100 None 1.000 15 0 2004 2019
Entrez Id: 1111
Gene Symbol: CHEK1
CHEK1 		O14757 checkpoint kinase 1 Kinase 195 0.492 0.808 3.1E-08 0.100 None 1.000 15 0 1999 2020
Entrez Id: 4683
Gene Symbol: NBN
NBN 		O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.100 None 1.000 14 0 1997 2011
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.100 None 1.000 12 0 1995 2018
Entrez Id: 54840
Gene Symbol: APTX
APTX 		Q7Z2E3 aprataxin Nucleic acid binding 94 0.590 0.500 4.0E-10 0.100 None 1.000 11 0 2000 2017
Entrez Id: 55655
Gene Symbol: NLRP2
NLRP2 		Q9NX02 NLR family pyrin domain containing 2 155 0.515 0.731 1.4E-38 0.100 None 1.000 10 0 2002 2011
Entrez Id: 4361
Gene Symbol: MRE11
MRE11 		P49959 MRE11 homolog, double strand break repair nuclease 171 0.527 0.808 1.3E-12 0.090 None 1.000 9 0 2003 2019
Entrez Id: 23650
Gene Symbol: TRIM29
TRIM29 		Q14134 tripartite motif containing 29 70 0.606 0.654 8.1E-08 0.080 None 1.000 8 0 1994 2019
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A 		P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.080 None 0.875 8 0 1995 2013
Entrez Id: 2395
Gene Symbol: FXN
FXN 		Q16595 frataxin Enzyme 220 0.510 0.654 0.34 0.070 None 0.857 7 0 1989 2011
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.070 None 1.000 7 0 2006 2019
Entrez Id: 9623
Gene Symbol: TCL1B
TCL1B 		O95988 T cell leukemia/lymphoma 1B 100 0.561 0.500 1.0E-02 0.070 None 0.857 7 0 1995 2004