Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 326
Gene Symbol: AIRE
AIRE 		O43918 autoimmune regulator 175 0.516 0.808 4.0E-12 0.100 None 0.980 101 5 1993 2019
Entrez Id: 115352
Gene Symbol: FCRL3
FCRL3 		Q96P31 Fc receptor like 3 Cell adhesion 62 0.612 0.769 6.0E-21 0.100 None 0.962 26 5 2005 2019
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109 		Q2LD37 KIAA1109 86 0.603 0.654 3.3E-21 0.120 None 1.000 3 5 2007 2014
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22 		Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 400 0.438 0.846 3.5E-21 0.500 None 0.948 213 4 2004 2019
Entrez Id: 7297
Gene Symbol: TYK2
TYK2 		P29597 tyrosine kinase 2 Kinase 172 0.505 0.769 4.5E-08 0.200 None 1.000 15 4 2005 2019
Entrez Id: 868
Gene Symbol: CBLB
CBLB 		Q13191 Cbl proto-oncogene B Enzyme 33 0.691 0.423 1.00 0.090 None 0.889 9 4 2004 2019
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3 		P68036 ubiquitin conjugating enzyme E2 L3 Enzyme 56 0.644 0.615 0.84 0.140 None 1.000 6 4 2011 2019
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1 		Q495T6 membrane metalloendopeptidase like 1 Enzyme 74 0.606 0.692 1.2E-22 0.100 None 1.000 1 4 2011 2011
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		P16410 cytotoxic T-lymphocyte associated protein 4 722 0.369 0.923 0.94 0.100 None 0.941 204 3 1996 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.100 None 0.957 47 3 2000 2019
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 316 0.471 0.769 0.77 0.200 None 0.956 45 3 2008 2019
Entrez Id: 3663
Gene Symbol: IRF5
IRF5 		Q13568 interferon regulatory factor 5 Transcription factor 226 0.489 0.731 9.0E-03 0.200 None 0.953 43 3 2006 2020
Entrez Id: 149233
Gene Symbol: IL23R
IL23R 		Q5VWK5 interleukin 23 receptor Signaling 306 0.466 0.769 5.6E-04 0.200 None 0.972 36 3 2007 2019
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.400 None 0.923 13 3 2004 2019
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2 		P17706 protein tyrosine phosphatase non-receptor type 2 134 0.538 0.692 1.00 0.200 None 1.000 12 3 2010 2019
Entrez Id: 919
Gene Symbol: CD247
CD247 		P20963 CD247 molecule 140 0.539 0.731 1.7E-02 0.190 None 1.000 10 3 2001 2017
Entrez Id: 117289
Gene Symbol: TAGAP
TAGAP 		Q8N103 T cell activation RhoGTPase activating protein Enzyme modulator 24 0.700 0.462 0.85 0.140 None 1.000 5 3 2010 2018
Entrez Id: 55024
Gene Symbol: BANK1
BANK1 		Q8NDB2 B cell scaffold protein with ankyrin repeats 1 51 0.653 0.538 4.8E-12 0.050 None 1.000 5 3 2011 2018
Entrez Id: 3654
Gene Symbol: IRAK1
IRAK1 		P51617 interleukin 1 receptor associated kinase 1 Kinase 200 0.506 0.808 0.99 0.040 None 1.000 4 3 2014 2019
Entrez Id: 150962
Gene Symbol: PUS10
PUS10 		Q3MIT2 pseudouridine synthase 10 17 0.736 0.346 7.9E-14 0.100 None 1.000 2 3 2011 2019
Entrez Id: 59338
Gene Symbol: PLEKHA1
PLEKHA1 		Q9HB21 pleckstrin homology domain containing A1 Epigenetic regulator 17 0.769 0.269 2.3E-04 0.100 None 1.000 2 3 2011 2019
Entrez Id: 200734
Gene Symbol: SPRED2
SPRED2 		Q7Z698 sprouty related EVH1 domain containing 2 Receptor 38 0.711 0.577 2.9E-07 0.100 None 1.000 1 3 2011 2011
Entrez Id: 55225
Gene Symbol: RAVER2
RAVER2 		Q9HCJ3 ribonucleoprotein, PTB binding 2 Nucleic acid binding 8 0.821 0.154 1.5E-08 0.010 None 1.000 1 3 2012 2012
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA 		P01589 interleukin 2 receptor subunit alpha Receptor 540 0.389 0.885 5.5E-02 0.200 None 0.960 75 2 2002 2020
Entrez Id: 958
Gene Symbol: CD40
CD40 		P25942 CD40 molecule 528 0.396 0.846 0.85 0.200 None 1.000 47 2 1996 2020