Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 1.000 definitive 0.994 170 109 1960 2020
Entrez Id: 51684
Gene Symbol: SUFU
SUFU
Q9UMX1 SUFU negative regulator of hedgehog signaling 272 0.493 0.769 1.00 1.000 None 0.938 16 12 2006 2018
Entrez Id: 8643
Gene Symbol: PTCH2
PTCH2
Q9Y6C5 patched 2 114 0.563 0.692 3.4E-16 0.770 limited 1.000 11 2 1985 2017
Entrez Id: 2736
Gene Symbol: GLI2
GLI2
P10070 GLI family zinc finger 2 351 0.446 0.846 0.97 0.300 None 1.000 1 0 2006 2006
Entrez Id: 5741
Gene Symbol: PTH
PTH
P01270 parathyroid hormone 528 0.397 0.846 1.2E-02 0.300 None 1.000 1 0 2014 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.060 None 1.000 6 0 1994 2015
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
P08151 GLI family zinc finger 1 369 0.431 0.846 7.7E-14 0.050 None 1.000 5 1 2004 2019
Entrez Id: 6608
Gene Symbol: SMO
SMO
Q99835 smoothened, frizzled class receptor G-protein coupled receptor 215 0.489 0.731 4.3E-07 0.040 None 1.000 4 0 2008 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.030 None 1.000 3 0 1999 2010
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.020 None 1.000 2 0 1987 2015
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.020 None 0.500 2 0 1999 2004
Entrez Id: 6469
Gene Symbol: SHH
SHH
Q15465 sonic hedgehog signaling molecule 303 0.461 0.846 0.98 0.020 None 1.000 2 0 1999 2002
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.020 None 1.000 2 0 1999 2002
Entrez Id: 4920
Gene Symbol: ROR2
ROR2
Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 250 0.498 0.731 1.2E-04 0.020 None 1.000 2 0 2003 2007
Entrez Id: 5726
Gene Symbol: TAS2R38
TAS2R38
P59533 taste 2 receptor member 38 G-protein coupled receptor 149 0.531 0.808 0.13 0.020 None 0.500 2 0 1999 2004
Entrez Id: 8030
Gene Symbol: CCDC6
CCDC6
Q16204 coiled-coil domain containing 6 156 0.517 0.808 0.58 0.020 None 0.500 2 0 1999 2004
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
P36897 transforming growth factor beta receptor 1 Kinase 347 0.451 0.885 0.85 0.020 None 1.000 2 0 1996 1996
Entrez Id: 2158
Gene Symbol: F9
F9
P00740 coagulation factor IX Enzyme 276 0.465 0.885 1.00 0.020 None 0.500 2 0 1999 2004
Entrez Id: 6613
Gene Symbol: SUMO2
SUMO2
P61956 small ubiquitin like modifier 2 42 0.666 0.615 0.87 0.010 None 1.000 1 0 2005 2005
Entrez Id: 8102
Gene Symbol: XRS
XRS
X-ray sensitivity 19 0.716 0.500 0.010 None < 0.001 1 0 1987 1987
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.010 None 1.000 1 0 2015 2015
Entrez Id: 353376
Gene Symbol: TICAM2
TICAM2
Q86XR7 Q9Y3B3 toll like receptor adaptor molecule 2 332 0.438 0.769 2.6E-03 0.010 None 1.000 1 0 1999 1999
Entrez Id: 5715
Gene Symbol: PSMD9
PSMD9
O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 344 0.435 0.846 4.9E-06 0.010 None 1.000 1 0 1999 1999
Entrez Id: 5266
Gene Symbol: PI3
PI3
P19957 peptidase inhibitor 3 Enzyme modulator 92 0.570 0.692 0.17 0.010 None 1.000 1 0 1996 1996
Entrez Id: 51715
Gene Symbol: RAB23
RAB23
Q9ULC3 RAB23, member RAS oncogene family 144 0.541 0.654 5.6E-03 0.010 None 1.000 1 0 2006 2006