Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 1.000 5 0 2004 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 270 0.248 0.962 0.32 0.400 None 1.000 2 0 2013 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.310 None 1.000 2 0 2013 2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.360 None 1.000 5 0 2004 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 179 0.287 0.962 3.7E-02 0.310 None 1.000 1 0 2001 2001
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 167 0.288 0.962 0.47 0.310 None 1.000 1 0 2012 2012
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.350 None 1.000 3 0 2000 2016
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.330 None 0.500 2 0 2009 2014
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 109 0.310 0.962 2.7E-04 0.330 None 1.000 1 0 2015 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 109 0.311 0.962 0.98 0.390 None 1.000 5 0 2003 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 119 0.318 0.885 0.27 0.340 None 1.000 2 0 2011 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 80 0.321 0.962 4.6E-09 0.330 None 1.000 1 0 2014 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 113 0.324 0.962 1.00 0.330 None 1.000 5 0 2000 2012
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 48 0.325 0.923 0.99 0.310 None 1.000 1 0 2012 2015
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 89 0.327 0.923 0.98 0.300 None 1.000 1 0 2013 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 101 0.328 0.923 1.0E-37 0.570 None 0.500 4 0 2000 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 69 0.330 0.923 1.00 0.330 None 1.000 1 0 2002 2018
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 68 0.333 0.923 1.1E-03 0.310 None 1.000 1 0 2013 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.600 None 1.000 6 0 2006 2015
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 115 0.338 0.962 1.9E-03 0.340 None 0.500 2 0 1997 2016
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 119 0.345 0.923 0.66 0.600 None 1.000 7 0 2002 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 42 0.352 0.885 1.7E-05 0.310 None 1.000 1 0 2012 2012
Entrez Id: 5443
Gene Symbol: POMC
POMC 		P01189 proopiomelanocortin 241 0.356 0.846 1.2E-04 0.520 None 1.000 3 0 1985 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		O60603 toll like receptor 2 34 0.361 0.923 1.0E-06 0.330 None 1.000 1 0 2014 2016
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 87 0.362 0.885 1.00 0.310 None 1.000 3 0 2009 2012