Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.400 None 0.947 19 1 2012 2019
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.400 None 0.941 17 1 2003 2019
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 391 0.440 0.808 1.00 0.400 None 0.875 16 0 1999 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.400 None 0.867 15 5 2005 2013
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.400 None 1.000 14 2 2009 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.400 None 0.833 12 0 2001 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.400 None 1.000 12 0 1997 2018
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.400 None 1.000 12 2 2004 2017
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.400 None 1.000 11 0 1996 2018
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
P07203 glutathione peroxidase 1 Enzyme 290 0.458 0.923 3.9E-05 0.400 None 0.909 11 3 2004 2017
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Q96KA5 CLPTM1 like Enzyme 110 0.551 0.654 4.4E-05 0.400 None 1.000 3 2 2009 2014
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.390 None 0.909 11 0 1987 2019
Entrez Id: 355
Gene Symbol: FAS
FAS
P25445 Fas cell surface death receptor 754 0.372 0.923 0.81 0.380 None 1.000 9 0 1997 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.370 None 1.000 8 0 2006 2019
Entrez Id: 406892
Gene Symbol: MIR100
MIR100
microRNA 100 146 0.521 0.846 0.370 None 1.000 8 0 2012 2018
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.370 None 1.000 8 0 2015 2020
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.370 None 1.000 7 0 2014 2019
Entrez Id: 688
Gene Symbol: KLF5
KLF5
Q13887 Kruppel like factor 5 Nucleic acid binding 143 0.534 0.769 0.82 0.370 None 1.000 7 0 2003 2017
Entrez Id: 898
Gene Symbol: CCNE1
CCNE1
P24864 cyclin E1 Enzyme modulator 133 0.538 0.731 0.97 0.370 None 1.000 7 1 2000 2019
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 Nuclear receptor 528 0.400 0.923 4.5E-08 0.360 None 1.000 7 0 2006 2019
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
P08151 GLI family zinc finger 1 369 0.431 0.846 7.7E-14 0.360 None 1.000 7 0 2002 2019
Entrez Id: 407026
Gene Symbol: MIR29C
MIR29C
microRNA 29c 183 0.496 0.808 0.360 None 1.000 7 0 2013 2018
Entrez Id: 407055
Gene Symbol: MIR99A
MIR99A
microRNA 99a 122 0.536 0.808 0.360 None 0.857 7 0 2014 2020
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
P19971 thymidine phosphorylase Enzyme 246 0.495 0.769 1.2E-04 0.340 None 1.000 6 0 1999 2009
Entrez Id: 79366
Gene Symbol: HMGN5
HMGN5
P82970 high mobility group nucleosome binding domain 5 42 0.650 0.423 0.31 0.340 None 0.800 5 0 2011 2018