Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
P42772 cyclin dependent kinase inhibitor 2B 440 0.417 0.769 7.3E-03 0.400 None 0.947 57 1 1995 2018
Entrez Id: 545
Gene Symbol: ATR
ATR
Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.400 None 0.965 57 0 1999 2020
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
P52926 high mobility group AT-hook 2 Nucleic acid binding 382 0.429 0.808 0.87 0.400 None 0.981 54 0 1998 2020
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.400 None 0.904 52 5 1994 2018
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 341 0.455 0.846 1.00 0.400 None 1.000 51 0 2004 2019
Entrez Id: 23405
Gene Symbol: DICER1
DICER1
Q9UPY3 dicer 1, ribonuclease III Enzyme 302 0.446 0.846 1.00 0.400 None 0.959 49 1 2007 2020
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.400 None 0.959 49 1 1989 2019
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
Q13421 mesothelin Extracellular structure 146 0.525 0.692 5.9E-25 0.400 None 1.000 48 0 2005 2019
Entrez Id: 641
Gene Symbol: BLM
BLM
P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.400 None 0.979 48 4 1999 2019
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
O14965 aurora kinase A Kinase 245 0.475 0.731 0.87 0.400 None 0.979 48 2 2004 2020
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2
P29317 EPH receptor A2 Kinase 187 0.501 0.731 1.1E-05 0.400 None 1.000 47 0 2002 2020
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.400 None 0.976 42 3 1997 2020
Entrez Id: 79727
Gene Symbol: LIN28A
LIN28A
Q9H9Z2 lin-28 homolog A Nucleic acid binding 161 0.523 0.731 1.9E-02 0.400 None 0.976 41 0 2009 2020
Entrez Id: 3606
Gene Symbol: IL18
IL18
Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.400 None 0.975 40 0 2000 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
P80188 lipocalin 2 Enzyme 497 0.405 0.885 1.1E-09 0.400 None 1.000 40 0 2005 2019
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
Q92911 solute carrier family 5 member 5 Transporter 195 0.499 0.769 2.9E-03 0.400 None 1.000 40 0 1999 2020
Entrez Id: 7486
Gene Symbol: WRN
WRN
Q14191 WRN RecQ like helicase Enzyme 172 0.524 0.808 2.6E-34 0.400 None 1.000 39 1 1999 2019
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
Q02750 mitogen-activated protein kinase kinase 1 Kinase 389 0.439 0.846 0.90 0.400 None 0.946 37 1 2002 2019
Entrez Id: 9582
Gene Symbol: APOBEC3B
APOBEC3B
Q9UH17 apolipoprotein B mRNA editing enzyme catalytic subunit 3B Enzyme 118 0.547 0.731 5.2E-16 0.400 None 0.973 37 1 2001 2019
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
Q00534 cyclin dependent kinase 6 Kinase 266 0.471 0.731 0.98 0.400 None 1.000 36 0 1995 2020
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
Q12882 dihydropyrimidine dehydrogenase Enzyme 249 0.493 0.846 3.4E-22 0.400 None 1.000 33 6 1997 2019
Entrez Id: 54658
Gene Symbol: UGT1A1
UGT1A1
P22309 UDP glucuronosyltransferase family 1 member A1 302 0.464 0.769 3.3E-06 0.400 None 1.000 32 0 2000 2019
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A
O00220 TNF receptor superfamily member 10a 155 0.521 0.731 5.1E-15 0.400 None 0.969 32 5 2000 2018
Entrez Id: 10395
Gene Symbol: DLC1
DLC1
Q96QB1 DLC1 Rho GTPase activating protein 144 0.529 0.731 1.00 0.400 None 0.968 31 0 2003 2020
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.400 None 0.903 31 1 1998 2019