Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5606
Gene Symbol: MAP2K3
MAP2K3 		P46734 mitogen-activated protein kinase kinase 3 Kinase 1 0.619 0.615 2.2E-02 0.300 None 0 2
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.400 None 0.960 4 0 1984 2019
Entrez Id: 2520
Gene Symbol: GAST
GAST 		P01350 gastrin 21 0.485 0.808 2.7E-03 0.400 None 0.929 1 0 1986 2017
Entrez Id: 4953
Gene Symbol: ODC1
ODC1 		P11926 ornithine decarboxylase 1 Enzyme 16 0.510 0.731 0.17 0.390 None 1.000 1 0 1987 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 31 0.399 0.808 3.4E-05 0.500 None 0.990 1 10 1988 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.979 2 0 1989 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.500 None 0.981 6 0 1991 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.500 None 0.966 3 1 1991 2020
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.500 None 0.948 7 4 1992 2019
Entrez Id: 6714
Gene Symbol: SRC
SRC 		P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 26 0.467 0.885 1.00 0.400 None 0.786 1 0 1992 2018
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 67 0.425 0.846 0.72 0.400 None 0.979 6 0 1993 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.400 None 1.000 3 0 1993 2020
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		P05362 intercellular adhesion molecule 1 57 0.364 0.962 3.5E-02 0.350 None 0.833 2 0 1993 2015
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 167 0.288 0.962 0.47 0.400 None 1.000 1 0 1993 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 1.000 2 0 1994 2020
Entrez Id: 5782
Gene Symbol: PTPN12
PTPN12 		Q05209 protein tyrosine phosphatase non-receptor type 12 2 0.641 0.769 1.00 0.510 None 1.000 1 1 1994 2018
Entrez Id: 4316
Gene Symbol: MMP7
MMP7 		P09237 matrix metallopeptidase 7 Enzyme 10 0.446 0.885 1.0E-09 0.400 None 1.000 1 0 1994 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.600 None 0.964 1 0 1995 2019
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 71 0.413 0.846 0.13 0.500 None 1.000 1 0 1995 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.946 3 0 1996 2019
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		P01344 insulin like growth factor 2 59 0.390 0.885 4.4E-02 0.400 None 0.875 1 0 1996 2017
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A 		P38936 cyclin dependent kinase inhibitor 1A 34 0.403 0.769 1.9E-03 0.400 None 0.941 1 0 1996 2019
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		P11166 solute carrier family 2 member 1 Transporter 94 0.388 0.808 0.99 0.380 None 1.000 1 0 1996 2020
Entrez Id: 1890
Gene Symbol: TYMP
TYMP 		P19971 thymidine phosphorylase Enzyme 23 0.495 0.769 1.2E-04 0.340 None 1.000 1 0 1996 2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.400 None 0.966 1 0 1996 2019