Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
Q12882 dihydropyrimidine dehydrogenase Enzyme 45 0.493 0.846 3.4E-22 0.330 None 1.000 1 0 2003 2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.400 None 0.971 0 2 2003 2019
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
P09917 arachidonate 5-lipoxygenase Enzyme 64 0.447 0.885 1.2E-06 0.370 None 0.889 3 0 2004 2018
Entrez Id: 3158
Gene Symbol: HMGCS2
HMGCS2
P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 7 0.666 0.577 4.3E-14 0.310 None 1.000 2 0 2004 2017
Entrez Id: 57381
Gene Symbol: RHOJ
RHOJ
Q9H4E5 ras homolog family member J Enzyme modulator 5 0.686 0.308 6.4E-03 0.300 None 1.000 1 0 2004 2004
Entrez Id: 5608
Gene Symbol: MAP2K6
MAP2K6
P52564 mitogen-activated protein kinase kinase 6 Kinase 6 0.631 0.615 0.91 0.320 None 1.000 1 0 2004 2014
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 36 0.474 0.808 1.3E-09 0.300 None 1.000 1 0 2004 2004
Entrez Id: 59
Gene Symbol: ACTA2
ACTA2
P62736 actin alpha 2, smooth muscle Cellular structure 40 0.508 0.846 0.93 0.300 None 1.000 1 0 2004 2004
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
P27338 monoamine oxidase B 35 0.533 0.808 1.00 0.300 None 1.000 1 0 2004 2004
Entrez Id: 57447
Gene Symbol: NDRG2
NDRG2
Q9UN36 NDRG family member 2 Enzyme 14 0.518 0.692 2.2E-05 0.330 None 1.000 1 0 2004 2014
Entrez Id: 4224
Gene Symbol: MEP1A
MEP1A
Q16819 meprin A subunit alpha Enzyme 2 0.780 0.231 9.2E-13 0.300 None 1.000 1 0 2004 2004
Entrez Id: 5268
Gene Symbol: SERPINB5
SERPINB5
P36952 serpin family B member 5 Enzyme modulator 13 0.582 0.577 3.6E-03 0.310 None 1.000 1 0 2004 2014
Entrez Id: 5121
Gene Symbol: PCP4
PCP4
P48539 Purkinje cell protein 4 2 0.682 0.423 2.2E-03 0.300 None 1.000 1 0 2004 2004
Entrez Id: 430
Gene Symbol: ASCL2
ASCL2
Q99929 achaete-scute family bHLH transcription factor 2 Transcription factor 2 0.691 0.423 0.35 0.350 None 0.833 1 0 2004 2019
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
Q12809 potassium voltage-gated channel subfamily H member 2 Ion channel 25 0.522 0.731 1.00 0.310 None 1.000 1 0 2004 2005
Entrez Id: 3679
Gene Symbol: ITGA7
ITGA7
Q13683 integrin subunit alpha 7 6 0.588 0.654 4.3E-17 0.300 None 1.000 1 0 2004 2004
Entrez Id: 2596
Gene Symbol: GAP43
GAP43
P17677 growth associated protein 43 20 0.564 0.731 2.1E-02 0.300 None 1.000 1 0 2004 2004
Entrez Id: 894
Gene Symbol: CCND2
CCND2
P30279 cyclin D2 Enzyme modulator 42 0.477 0.808 0.99 0.610 None 1.000 1 3 2004 2019
Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
Q9NQ66 phospholipase C beta 1 Enzyme 19 0.595 0.654 0.98 0.300 None 1.000 1 0 2004 2004
Entrez Id: 6941
Gene Symbol: TCF19
TCF19
Q9Y242 transcription factor 19 3 0.674 0.692 9.4E-04 0.300 None 1.000 1 0 2004 2004
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1
P54289 calcium voltage-gated channel auxiliary subunit alpha2delta 1 Ion channel 39 0.641 0.500 1.00 0.300 None 1.000 1 0 2004 2004
Entrez Id: 72
Gene Symbol: ACTG2
ACTG2
P63267 actin gamma 2, smooth muscle Cellular structure 6 0.505 0.808 7.1E-02 0.300 None 1.000 1 0 2004 2004
Entrez Id: 2
Gene Symbol: A2M
A2M
P01023 alpha-2-macroglobulin Enzyme modulator 26 0.529 0.769 4.5E-11 0.310 None 1.000 1 0 2004 2019
Entrez Id: 4321
Gene Symbol: MMP12
MMP12
P39900 matrix metallopeptidase 12 Enzyme 15 0.484 0.885 0.300 None 1.000 1 0 2004 2004
Entrez Id: 7490
Gene Symbol: WT1
WT1
P19544 WT1 transcription factor Nucleic acid binding 54 0.422 0.808 1.00 0.320 None 1.000 1 0 2004 2019