Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 894
Gene Symbol: CCND2
CCND2 		P30279 cyclin D2 Enzyme modulator 172 0.477 0.808 0.99 0.610 None 1.000 1 0 2004 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.600 None 0.964 81 3 1995 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 698 0.358 0.885 2.9E-02 0.600 None 1.000 42 2 1998 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.600 None 1.000 30 0 1997 2019
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A 		O00220 TNF receptor superfamily member 10a 126 0.521 0.731 5.1E-15 0.520 None 1.000 2 0 2006 2019
Entrez Id: 5782
Gene Symbol: PTPN12
PTPN12 		Q05209 protein tyrosine phosphatase non-receptor type 12 47 0.641 0.769 1.00 0.510 None 1.000 1 0 1994 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.500 None 0.966 233 9 1991 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.500 None 0.981 149 5 1991 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 446 0.399 0.808 3.4E-05 0.500 None 0.990 96 7 1988 2020
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 517 0.373 0.962 1.00 0.500 None 0.948 89 6 1992 2019
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 307 0.413 0.846 0.13 0.500 None 1.000 17 0 1995 2017
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 130 0.521 0.769 1.3E-18 0.500 None 1.000 11 4 2005 2018
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2 		Q9NQB0 transcription factor 7 like 2 192 0.485 0.846 1.00 0.480 None 1.000 8 1 2005 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 220 0.460 0.808 1.2E-24 0.470 None 0.857 7 1 2001 2009
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2 		Q9Y2T1 axin 2 145 0.507 0.692 0.57 0.470 None 1.000 7 0 2001 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.400 None 0.995 194 1 1997 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.400 None 0.946 108 1 1996 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.400 None 0.971 104 4 2003 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.400 None 0.979 95 6 1989 2019
Entrez Id: 8842
Gene Symbol: PROM1
PROM1 		O43490 prominin 1 Transporter 412 0.410 0.846 1.9E-22 0.400 None 0.961 50 0 2007 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.400 None 0.978 44 1 2005 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 356 0.425 0.846 0.72 0.400 None 0.979 44 1 1993 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.400 None 1.000 37 0 1994 2020
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		P50591 TNF superfamily member 10 Signaling 412 0.413 0.885 0.13 0.400 None 1.000 35 0 2000 2019
Entrez Id: 1045
Gene Symbol: CDX2
CDX2 		Q99626 caudal type homeobox 2 Transcription factor 267 0.458 0.769 0.53 0.400 None 0.909 32 0 1999 2019