Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.100 None 0.975 40 1 1987 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.510 None 1.000 2 0 1987 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.881 42 3 1994 2020
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.370 None 1.000 9 1 1994 2018
Entrez Id: 4163
Gene Symbol: MCC
MCC
P23508 MCC regulator of WNT signaling pathway 110 0.568 0.731 4.7E-16 0.300 None 1.000 1 0 1994 1994
Entrez Id: 4320
Gene Symbol: MMP11
MMP11
P24347 matrix metallopeptidase 11 Enzyme 130 0.542 0.692 2.4E-05 0.010 None 1.000 1 0 1996 1996
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
P35900 keratin 20 559 0.388 0.846 9.1E-11 0.020 None 1.000 2 0 1997 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.100 None 0.923 13 2 1998 2014
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.100 None 0.909 11 0 1998 2015
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
P09237 matrix metallopeptidase 7 Enzyme 320 0.446 0.885 1.0E-09 0.060 None 1.000 6 0 1998 2018
Entrez Id: 4830
Gene Symbol: NME1
NME1
P15531 NME/NM23 nucleoside diphosphate kinase 1 Kinase 329 0.443 0.808 3.2E-03 0.010 None 1.000 1 0 1998 1998
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
Q8TD31 coiled-coil alpha-helical rod protein 1 193 0.505 0.808 1.0E-16 0.010 None 1.000 1 0 1998 1998
Entrez Id: 27102
Gene Symbol: EIF2AK1
EIF2AK1
Q9BQI3 eukaryotic translation initiation factor 2 alpha kinase 1 Kinase 56 0.633 0.577 7.0E-07 0.010 None 1.000 1 0 1998 1998
Entrez Id: 9034
Gene Symbol: CCRL2
CCRL2
O00421 C-C motif chemokine receptor like 2 G-protein coupled receptor 59 0.621 0.654 0.37 0.010 None 1.000 1 0 1998 1998
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.050 None 1.000 5 0 1999 2013
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.040 None 1.000 4 1 1999 2013
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
P05091 aldehyde dehydrogenase 2 family member Enzyme 337 0.457 0.885 3.4E-10 0.030 None 1.000 3 1 1999 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.020 None 1.000 2 0 1999 2017
Entrez Id: 699
Gene Symbol: BUB1
BUB1
O43683 BUB1 mitotic checkpoint serine/threonine kinase Kinase 162 0.528 0.731 4.9E-09 0.010 None 1.000 1 0 1999 1999
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9
Q6ZT07 TBC1 domain family member 9 Enzyme 491 0.399 0.846 2.8E-05 0.010 None 1.000 1 0 1999 1999
Entrez Id: 2191
Gene Symbol: FAP
FAP
Q12884 fibroblast activation protein alpha Enzyme 216 0.496 0.808 1.9E-28 0.010 None 1.000 1 0 1999 1999
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.090 None 1.000 9 1 2000 2010
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.060 None 0.833 6 0 2000 2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.020 None 1.000 2 0 2000 2009
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.400 None 0.947 19 0 2001 2017