Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.400 None 1.000 83 5 1996 2019
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3
O43542 X-ray repair cross complementing 3 184 0.505 0.769 1.9E-10 0.060 None 0.833 6 5 2009 2017
Entrez Id: 3606
Gene Symbol: IL18
IL18
Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.010 None 1.000 1 5 2015 2015
Entrez Id: 101928337
Gene Symbol: PTCSC2
PTCSC2
papillary thyroid carcinoma susceptibility candidate 2 22 0.751 0.231 0.010 None 1.000 1 5 2017 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.917 12 4 2005 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.030 None 1.000 3 4 2015 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.906 32 3 1993 2018
Entrez Id: 2304
Gene Symbol: FOXE1
FOXE1
O00358 forkhead box E1 Transcription factor 102 0.573 0.731 0.79 0.100 None 1.000 16 3 2001 2020
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.080 None 0.875 8 3 2012 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.330 None 1.000 3 3 2015 2017
Entrez Id: 59067
Gene Symbol: IL21
IL21
Q9HBE4 interleukin 21 321 0.441 0.769 0.63 0.010 None 1.000 1 3 2014 2014
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.400 None 0.994 159 2 2003 2019
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.100 None 0.962 26 2 1998 2018
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.100 None 0.958 24 2 2004 2020
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.050 None 1.000 5 2 1990 2018
Entrez Id: 3026
Gene Symbol: HABP2
HABP2
Q14520 hyaluronan binding protein 2 Enzyme 88 0.593 0.615 2.0E-15 0.040 None 1.000 4 2 2015 2017
Entrez Id: 6392
Gene Symbol: SDHD
SDHD
O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.020 None 1.000 2 2 2015 2017
Entrez Id: 7850
Gene Symbol: IL1R2
IL1R2
P27930 interleukin 1 receptor type 2 Receptor 76 0.593 0.846 6.5E-15 0.010 None 1.000 1 2 2019 2019
Entrez Id: 5795
Gene Symbol: PTPRJ
PTPRJ
Q12913 protein tyrosine phosphatase receptor type J Enzyme 79 0.606 0.615 1.3E-11 0.010 None 1.000 1 2 2004 2004
Entrez Id: 7038
Gene Symbol: TG
TG
P01266 thyroglobulin Enzyme modulator 240 0.480 0.808 2.9E-59 0.100 None 0.917 48 1 1985 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 1.000 35 1 2005 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 32 1 2005 2019
Entrez Id: 8030
Gene Symbol: CCDC6
CCDC6
Q16204 coiled-coil domain containing 6 156 0.517 0.808 0.58 0.100 None 1.000 23 1 1996 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 1.000 16 1 1997 2019
Entrez Id: 27352
Gene Symbol: SGSM3
SGSM3
Q96HU1 small G protein signaling modulator 3 Enzyme 259 0.469 0.808 3.4E-15 0.070 None 1.000 7 1 2007 2017