Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.500 None 1.000 127 17 2002 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.500 None 1.000 120 2 1998 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 110 7 2003 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 64 0 2000 2020
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.400 None 1.000 62 0 2010 2020
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.100 None 1.000 46 0 2010 2020
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.100 None 1.000 42 1 2002 2020
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.100 None 1.000 41 2 1998 2019
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.100 None 1.000 36 0 2007 2020
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.400 None 1.000 36 3 1995 2019
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1
P43699 NK2 homeobox 1 Transcription factor 319 0.457 0.808 0.36 0.400 None 1.000 35 0 1996 2020
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 336 0.435 0.846 0.100 None 1.000 32 0 2003 2020
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
microRNA 34a 428 0.421 0.846 0.100 None 1.000 32 0 2009 2020
Entrez Id: 7431
Gene Symbol: VIM
VIM
P08670 vimentin 644 0.372 0.846 0.71 0.100 None 1.000 31 0 2010 2019
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 Signaling 445 0.413 0.885 0.13 0.100 None 1.000 31 0 2002 2019
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
Q08050 forkhead box M1 323 0.441 0.769 7.4E-04 0.400 None 1.000 29 0 2008 2020
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.400 None 1.000 29 0 2006 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.400 None 1.000 29 4 1999 2018
Entrez Id: 558
Gene Symbol: AXL
AXL
P30530 AXL receptor tyrosine kinase Kinase 203 0.489 0.615 1.3E-02 0.400 None 1.000 29 1 2011 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.100 None 1.000 29 1 2000 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 1.000 28 0 2004 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.100 None 1.000 28 0 2002 2019
Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
Q14145 kelch like ECH associated protein 1 251 0.475 0.808 3.9E-04 0.400 None 1.000 28 0 2006 2020
Entrez Id: 10381
Gene Symbol: TUBB3
TUBB3
Q13509 tubulin beta 3 class III Cellular structure 259 0.486 0.808 2.6E-10 0.100 None 1.000 27 0 2005 2020
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
P49789 fragile histidine triad diadenosine triphosphatase 337 0.444 0.846 5.7E-03 0.400 None 1.000 27 0 1997 2017