Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.100 None 1.000 70 3 2000 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2 		P60568 interleukin 2 950 0.336 0.885 0.48 0.100 None 1.000 52 0 1990 2019
Entrez Id: 768
Gene Symbol: CA9
CA9 		Q16790 carbonic anhydrase 9 226 0.483 0.731 1.3E-09 0.100 None 1.000 51 0 1988 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.500 None 1.000 40 7 2006 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 1.000 38 0 2006 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.100 None 1.000 36 0 2006 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 36 0 2006 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.700 None 1.000 35 3 1998 2020
Entrez Id: 7942
Gene Symbol: TFEB
TFEB 		P19484 transcription factor EB 150 0.527 0.731 0.90 0.100 None 1.000 35 0 2003 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 28 0 1992 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.200 None 1.000 24 0 2000 2020
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		microRNA 21 726 0.363 0.846 0.100 None 1.000 24 0 2011 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.300 None 1.000 23 0 1991 2019
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1 		Q86U86 polybromo 1 Epigenetic regulator 105 0.566 0.615 1.00 0.400 None 1.000 23 0 2011 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.200 None 1.000 22 0 2007 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 1.000 22 0 1992 2020
Entrez Id: 29072
Gene Symbol: SETD2
SETD2 		Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 447 0.424 0.846 1.00 0.400 None 1.000 21 0 2004 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.100 None 1.000 21 1 1994 2019
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		P49815 TSC complex subunit 2 Enzyme modulator 410 0.439 0.808 1.00 0.400 None 1.000 21 0 1994 2020
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1 		Q15116 programmed cell death 1 497 0.402 0.846 0.42 0.100 None 1.000 19 0 2016 2020
Entrez Id: 7431
Gene Symbol: VIM
VIM 		P08670 vimentin 644 0.372 0.846 0.71 0.100 None 1.000 17 0 1999 2019
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.100 None 1.000 16 0 2004 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.300 None 1.000 16 0 1985 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.200 None 1.000 16 2 2003 2020
Entrez Id: 7248
Gene Symbol: TSC1
TSC1 		Q92574 TSC complex subunit 1 391 0.440 0.808 1.00 0.500 None 1.000 16 0 1995 2020