Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 201163
Gene Symbol: FLCN
FLCN
Q8NFG4 folliculin 30 0.537 0.885 0.79 0.900 strong 0.920 2 0 2002 2020
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 47 0.443 0.846 8.0E-02 0.700 strong 0.970 10 5 1989 2019
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1
Q99814 endothelial PAS domain protein 1 Transcription factor 14 0.454 0.731 0.60 0.700 None 0.974 1 18 2001 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.700 None 1.000 1 2 1998 2020
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 45 0.453 0.808 3.9E-12 0.620 None 1.000 0 0 2003 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.600 None 1.000 1 0 2002 2019
Entrez Id: 4771
Gene Symbol: NF2
NF2
P35240 neurofibromin 2 54 0.468 0.885 1.00 0.510 None 1.000 1 0 2012 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.500 None 0.900 4 26 1991 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 108 0.454 0.731 0.99 0.500 None 0.967 4 1 2011 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.500 None 1.000 1 7 2006 2019
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 74 0.440 0.808 1.00 0.500 None 1.000 1 0 1995 2020
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 68 0.343 0.885 1.00 0.500 None 0.983 1 7 2004 2020
Entrez Id: 4286
Gene Symbol: MITF
MITF
O75030 melanocyte inducing transcription factor 37 0.499 0.808 0.98 0.500 None 1.000 1 0 2003 2019
Entrez Id: 7030
Gene Symbol: TFE3
TFE3
P19532 transcription factor binding to IGHM enhancer 3 9 0.542 0.654 0.98 0.500 None 0.983 0 0 1996 2020
Entrez Id: 6921
Gene Symbol: ELOC
ELOC
Q15369 elongin C Enzyme modulator 6 0.656 0.500 0.74 0.460 None 1.000 1 2 2013 2019
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
P35680 HNF1 homeobox B Nucleic acid binding 22 0.473 0.808 1.00 0.450 None 0.800 0 0 1999 2017
Entrez Id: 84925
Gene Symbol: SLC49A4
SLC49A4
Q96SL1 solute carrier family 49 member 4 Transporter 7 0.780 0.231 2.3E-09 0.430 None 1.000 0 0 2002 2017
Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
Q14145 kelch like ECH associated protein 1 29 0.475 0.808 3.9E-04 0.420 None 1.000 1 0 2013 2019
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A Nucleic acid binding 28 0.478 0.846 0.96 0.420 None 1.000 0 0 1994 1999
Entrez Id: 11236
Gene Symbol: RNF139
RNF139
Q8WU17 ring finger protein 139 7 0.670 0.423 0.54 0.410 None 1.000 0 0 2005 2005
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
Q86U86 polybromo 1 Epigenetic regulator 20 0.566 0.615 1.00 0.400 None 1.000 2 0 2011 2019
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 28 0.424 0.846 1.00 0.400 None 1.000 2 0 2004 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 52 0.393 0.923 1.5E-04 0.400 None 1.000 2 0 1997 2018
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
P08729 keratin 7 18 0.463 0.808 3.1E-12 0.400 None 0.923 2 0 2004 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 61 0.380 0.923 2.1E-03 0.400 None 0.938 2 0 1997 2018