Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.700 None 0.960 230 0 1994 2020
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 283 0.420 0.846 7.1E-20 0.700 None 1.000 9 3 2002 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.600 None 0.950 519 10 1990 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 457 0.378 0.885 8.0E-02 0.600 None 1.000 34 0 1986 2016
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		P46531 notch receptor 1 581 0.369 0.885 1.00 0.600 None 0.935 30 0 2007 2019
Entrez Id: 355
Gene Symbol: FAS
FAS 		P25445 Fas cell surface death receptor 526 0.372 0.923 0.81 0.600 None 0.917 8 0 1999 2014
Entrez Id: 7508
Gene Symbol: XPC
XPC 		Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 129 0.504 0.808 3.7E-11 0.560 None 0.714 5 2 2005 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.500 None 0.979 266 8 1984 2020
Entrez Id: 4921
Gene Symbol: DDR2
DDR2 		Q16832 discoidin domain receptor tyrosine kinase 2 Kinase 91 0.541 0.769 0.55 0.500 None 1.000 10 4 2008 2018
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		Q9NZC7 WW domain containing oxidoreductase Enzyme 193 0.453 0.808 1.2E-15 0.460 None 1.000 6 0 2002 2018
Entrez Id: 51151
Gene Symbol: SLC45A2
SLC45A2 		Q9UMX9 solute carrier family 45 member 2 Transporter 40 0.626 0.538 1.7E-06 0.410 None 1.000 1 1 2009 2019
Entrez Id: 8626
Gene Symbol: TP63
TP63 		Q9H3D4 tumor protein p63 Transcription factor 553 0.362 0.769 1.00 0.400 None 0.963 76 1 2001 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.400 None 0.988 74 0 1989 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.400 None 1.000 67 3 2001 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.400 None 0.987 59 0 1997 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.400 None 0.972 55 1 1996 2019
Entrez Id: 6657
Gene Symbol: SOX2
SOX2 		P48431 SRY-box transcription factor 2 Transcription factor 421 0.405 0.808 0.71 0.400 None 1.000 41 0 2009 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.400 None 1.000 38 2 1985 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 581 0.380 0.923 2.1E-03 0.400 None 0.927 37 0 1993 2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.400 None 0.976 34 0 2002 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.400 None 1.000 27 2 2002 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.400 None 0.971 25 1 2001 2019
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 470 0.362 0.885 1.00 0.400 None 0.917 22 0 2008 2018
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 501 0.380 0.846 0.97 0.400 None 0.917 22 1 1997 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 935 0.330 0.923 1.00 0.400 None 0.962 20 1 2001 2020