Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.400 None 0.955 265 1 2000 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.400 None 0.956 203 8 1994 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.500 None 0.953 169 2 1995 2020
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.500 None 0.964 165 2 1995 2020
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.100 None 0.973 149 0 1994 2020
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.100 None 0.977 130 3 2004 2019
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.200 None 0.963 107 5 2007 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 0.929 99 4 2002 2020
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.400 None 0.923 91 6 1996 2020
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.400 None 0.976 83 3 1995 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.950 80 2 2001 2020
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.500 None 0.974 76 5 1997 2020
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.400 None 0.986 71 2 1999 2020
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.100 None 0.955 66 2 1995 2019
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.200 None 1.000 62 7 1995 2020
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.400 None 0.914 58 5 2002 2020
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.400 None 0.965 57 1 1993 2020
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.500 None 1.000 52 5 1995 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.100 None 0.962 52 1 2001 2020
Entrez Id: 6524
Gene Symbol: SLC5A2
SLC5A2
P31639 solute carrier family 5 member 2 Transporter 214 0.499 0.769 4.9E-14 0.100 None 0.942 52 0 2017 2020
Entrez Id: 8074
Gene Symbol: FGF23
FGF23
Q9GZV9 fibroblast growth factor 23 Signaling 305 0.460 0.731 3.1E-02 0.100 None 0.958 48 0 2013 2020
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.100 None 0.881 42 3 1995 2019
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
Q99988 growth differentiation factor 15 Signaling 389 0.429 0.808 3.0E-07 0.100 None 0.952 42 1 2002 2020
Entrez Id: 1803
Gene Symbol: DPP4
DPP4
P27487 dipeptidyl peptidase 4 Enzyme 451 0.420 0.808 7.3E-09 0.100 None 0.976 41 0 2009 2019
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
P04278 sex hormone binding globulin 368 0.438 0.808 1.3E-06 0.100 None 0.949 39 0 2006 2020