Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5972
Gene Symbol: REN
REN 		P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.100 None 0.973 149 0 1994 2020
Entrez Id: 6524
Gene Symbol: SLC5A2
SLC5A2 		P31639 solute carrier family 5 member 2 Transporter 214 0.499 0.769 4.9E-14 0.100 None 0.942 52 0 2017 2020
Entrez Id: 8074
Gene Symbol: FGF23
FGF23 		Q9GZV9 fibroblast growth factor 23 Signaling 305 0.460 0.731 3.1E-02 0.100 None 0.958 48 0 2013 2020
Entrez Id: 1803
Gene Symbol: DPP4
DPP4 		P27487 dipeptidyl peptidase 4 Enzyme 451 0.420 0.808 7.3E-09 0.100 None 0.976 41 0 2009 2019
Entrez Id: 6462
Gene Symbol: SHBG
SHBG 		P04278 sex hormone binding globulin 368 0.438 0.808 1.3E-06 0.100 None 0.949 39 0 2006 2020
Entrez Id: 260431
Gene Symbol: COPD
COPD 		Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 0.970 33 0 2009 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.100 None 1.000 30 0 1999 2020
Entrez Id: 79813
Gene Symbol: EHMT1
EHMT1 		Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 371 0.460 0.808 1.00 0.100 None 0.931 29 0 2013 2020
Entrez Id: 2641
Gene Symbol: GCG
GCG 		P01275 glucagon 441 0.431 0.885 3.5E-02 0.100 None 0.929 28 0 2013 2019
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R 		P43220 glucagon like peptide 1 receptor G-protein coupled receptor 288 0.471 0.846 0.29 0.100 None 0.893 28 0 2013 2019
Entrez Id: 3240
Gene Symbol: HP
HP 		P00738 haptoglobin Enzyme 464 0.412 0.885 1.7E-05 0.400 None 0.963 27 0 1997 2019
Entrez Id: 4306
Gene Symbol: NR3C2
NR3C2 		P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 287 0.469 0.846 0.84 0.100 None 1.000 26 0 2008 2020
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B 		O00300 TNF receptor superfamily member 11b 443 0.422 0.808 0.16 0.100 None 1.000 26 0 2004 2019
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1 		Q8TD31 coiled-coil alpha-helical rod protein 1 193 0.505 0.808 1.0E-16 0.100 None 1.000 25 0 2017 2020
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1 		Q13228 selenium binding protein 1 Immune response 214 0.493 0.846 3.2E-16 0.100 None 1.000 25 0 2017 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 24 0 1998 2020
Entrez Id: 9365
Gene Symbol: KL
KL 		Q9UEF7 klotho Enzyme 332 0.448 0.769 2.2E-04 0.100 None 1.000 24 0 2006 2020
Entrez Id: 5741
Gene Symbol: PTH
PTH 		P01270 parathyroid hormone 528 0.397 0.846 1.2E-02 0.100 None 1.000 22 0 2011 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.100 None 1.000 21 0 2009 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.400 None 0.952 21 0 2003 2020
Entrez Id: 8862
Gene Symbol: APLN
APLN 		Q9ULZ1 apelin 226 0.497 0.769 0.46 0.100 None 1.000 21 0 2009 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		P09601 heme oxygenase 1 666 0.381 0.923 9.7E-03 0.100 None 0.833 18 0 2005 2020
Entrez Id: 133
Gene Symbol: ADM
ADM 		P35318 adrenomedullin Signaling 405 0.436 0.808 4.1E-02 0.100 None 1.000 17 0 1999 2019
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3 		P17931 galectin 3 Signaling 557 0.392 0.846 2.3E-05 0.100 None 0.941 17 0 2013 2020
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.100 None 0.882 17 0 2007 2020