Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 842
Gene Symbol: CASP9
CASP9
P55211 caspase 9 Enzyme 293 0.458 0.808 7.4E-06 0.500 None 1.000 3 0 2001 2011
Entrez Id: 718
Gene Symbol: C3
C3
P01024 complement C3 Enzyme modulator 343 0.445 0.885 0.90 0.500 None 1.000 2 0 2011 2013
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2
O43464 HtrA serine peptidase 2 151 0.542 0.692 3.6E-03 0.500 None 1.000 2 0 2004 2009
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.310 None 1.000 2 0 2001 2017
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.310 None 1.000 2 0 2013 2017
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.300 None 1.000 4 0 2003 2007
Entrez Id: 134
Gene Symbol: ADORA1
ADORA1
P30542 adenosine A1 receptor G-protein coupled receptor 121 0.578 0.692 1.5E-02 0.300 None 1.000 1 0 2013 2013
Entrez Id: 3611
Gene Symbol: ILK
ILK
Q13418 integrin linked kinase Kinase 192 0.503 0.769 3.8E-05 0.300 None 1.000 1 0 2004 2004
Entrez Id: 57447
Gene Symbol: NDRG2
NDRG2
Q9UN36 NDRG family member 2 Enzyme 156 0.518 0.692 2.2E-05 0.300 None 1.000 1 0 2013 2013
Entrez Id: 572
Gene Symbol: BAD
BAD
Q92934 BCL2 associated agonist of cell death 125 0.553 0.769 4.6E-03 0.300 None 1.000 1 0 2003 2003
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
P37023 activin A receptor like type 1 Kinase 224 0.493 0.769 9.7E-04 0.300 None 1.000 1 0 2005 2005
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
P99999 cytochrome c, somatic 67 0.599 0.769 0.64 0.300 None 1.000 1 0 2001 2001
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.300 None 1.000 1 0 2007 2007
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.240 None 1.000 5 0 2000 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.220 None 1.000 5 0 2001 2017
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.220 None 1.000 5 0 2008 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.220 None 0.750 4 0 2001 2018
Entrez Id: 7450
Gene Symbol: VWF
VWF
P04275 von Willebrand factor Enzyme modulator 498 0.408 0.885 3.2E-25 0.220 None 1.000 3 0 2012 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.210 None 1.000 3 0 2013 2017
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.210 None 1.000 3 0 2001 2018
Entrez Id: 4502
Gene Symbol: MT2A
MT2A
P02795 metallothionein 2A 117 0.553 0.808 1.2E-05 0.210 None 1.000 2 0 2000 2007
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator Signaling 420 0.417 0.885 0.32 0.210 None 1.000 2 0 2011 2017
Entrez Id: 27113
Gene Symbol: BBC3
BBC3
Q96PG8 Q9BXH1 BCL2 binding component 3 157 0.517 0.769 4.0E-03 0.210 None 1.000 2 0 2003 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.210 None 1.000 2 0 2016 2020
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
P00750 plasminogen activator, tissue type Enzyme 392 0.445 0.885 5.7E-05 0.210 None 1.000 2 0 2005 2017