Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2
O43464 HtrA serine peptidase 2 chaperone; hydrolase; protease 90 0.582 0.448 3.7E-03 0.500 2 0 2004 2009
Entrez Id: 842
Gene Symbol: CASP9
CASP9
P55211 caspase 9 enzyme modulator; hydrolase; protease 140 0.516 0.724 8.2E-06 0.500 2 0 2001 2012
Entrez Id: 718
Gene Symbol: C3
C3
P01024 complement C3 defense/immunity protein; enzyme modulator; signaling molecule 187 0.484 0.828 0.94 0.500 2 0 2012 2013
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 oxidoreductase 456 0.406 0.931 0.13 0.300 4 0 2003 2007
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.300 1 0 2001 2001
Entrez Id: 57447
Gene Symbol: NDRG2
NDRG2
Q9UN36 NDRG family member 2 hydrolase; protease 95 0.558 0.621 9.5E-05 0.300 1 0 2013 2013
Entrez Id: 572
Gene Symbol: BAD
BAD
Q92934 BCL2 associated agonist of cell death 77 0.579 0.552 4.9E-03 0.300 1 0 2003 2003
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
P99999 cytochrome c, somatic 32 0.667 0.483 0.65 0.300 1 0 2001 2001
Entrez Id: 134
Gene Symbol: ADORA1
ADORA1
P30542 adenosine A1 receptor receptor 67 0.616 0.552 1.7E-02 0.300 1 0 2013 2013
Entrez Id: 3611
Gene Symbol: ILK
ILK
Q13418 integrin linked kinase 123 0.534 0.690 1.8E-05 0.300 1 0 2005 2005
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.250 1.000 6 0 2000 2015
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.210 1.000 4 0 2002 2017
Entrez Id: 4502
Gene Symbol: MT2A
MT2A
P02795 metallothionein 2A 75 0.588 0.621 1.4E-05 0.210 1.000 2 0 2000 2007
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma nucleic acid binding; receptor; transcription factor 540 0.388 0.828 0.14 0.200 3 0 2008 2009
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
P15559 NAD(P)H quinone dehydrogenase 1 230 0.467 0.724 1.0E-09 0.200 3 0 2017 2017
Entrez Id: 58157
Gene Symbol: NGB
NGB
Q9NPG2 neuroglobin transporter 30 0.681 0.310 4.2E-03 0.200 3 0 2003 2013
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.200 3 0 2006 2012
Entrez Id: 7225
Gene Symbol: TRPC6
TRPC6
Q9Y210 transient receptor potential cation channel subfamily C member 6 transporter 85 0.567 0.552 2.9E-07 0.200 2 0 2010 2014
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.200 2 0 2013 2014
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.200 2 0 2002 2014
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.200 2 0 2014 2015
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 signaling molecule 691 0.353 0.897 0.62 0.200 2 0 1995 2011
Entrez Id: 3297
Gene Symbol: HSF1
HSF1
Q00613 heat shock transcription factor 1 transcription factor 101 0.552 0.655 0.95 0.200 2 0 2014 2015
Entrez Id: 5724
Gene Symbol: PTAFR
PTAFR
P25105 platelet activating factor receptor receptor 38 0.639 0.552 0.20 0.200 2 0 1994 2007
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase hydrolase; protease 325 0.434 0.690 2.1E-06 0.200 2 0 2010 2011