Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2074
Gene Symbol: ERCC6
ERCC6
P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 257 0.507 0.808 5.2E-22 0.900 strong 0.989 89 3 1982 2020
Entrez Id: 1161
Gene Symbol: ERCC8
ERCC8
Q13216 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 175 0.551 0.885 2.8E-15 0.800 strong 0.978 46 1 1996 2020
Entrez Id: 83932
Gene Symbol: SPRTN
SPRTN
Q9H040 SprT-like N-terminal domain 44 0.691 0.500 0.97 0.310 limited 1.000 1 0 2014 2014
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.200 None 1.000 2 0 2011 2012
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.200 None 1.000 1 0 2014 2014
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1
Q8N653 leucine zipper like transcription regulator 1 152 0.547 0.808 1.0E-92 0.200 None 1.000 1 0 2018 2018
Entrez Id: 6016
Gene Symbol: RIT1
RIT1
Q92963 Ras like without CAAX 1 Enzyme modulator 184 0.527 0.808 0.13 0.200 None 1.000 1 0 2019 2019
Entrez Id: 6654
Gene Symbol: SOS1
SOS1
Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 0.200 None 1.000 1 0 2010 2010
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.200 None 1.000 1 0 2004 2004
Entrez Id: 545
Gene Symbol: ATR
ATR
Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.200 None 0 0
Entrez Id: 80254
Gene Symbol: CEP63
CEP63
Q96MT8 centrosomal protein 63 Cellular structure 44 0.666 0.500 6.2E-25 0.200 None 0 0
Entrez Id: 55835
Gene Symbol: CENPJ
CENPJ
Q9HC77 centromere protein J Enzyme 150 0.546 0.846 2.1E-27 0.200 None 0 0
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.140 None 0.750 4 2 1995 2017
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4
Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 325 0.468 0.846 1.4E-12 0.130 None 1.000 8 2 2008 2018
Entrez Id: 1442
Gene Symbol: CSH1
CSH1
P0DML2 P0DML3 chorionic somatomammotropin hormone 1 Signaling 105 0.566 0.808 2.1E-05 0.100 None 0.984 64 0 1996 2020
Entrez Id: 1443
Gene Symbol: CSH2
CSH2
P0DML2 P0DML3 chorionic somatomammotropin hormone 2 Signaling 104 0.566 0.808 1.3E-02 0.100 None 0.984 64 0 1996 2020
Entrez Id: 3313
Gene Symbol: HSPA9
HSPA9
P38646 heat shock protein family A (Hsp70) member 9 198 0.502 0.885 0.97 0.100 None 0.962 26 0 1998 2020
Entrez Id: 2071
Gene Symbol: ERCC3
ERCC3
P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 253 0.504 0.846 3.4E-11 0.100 None 1.000 25 0 1990 2019
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.100 None 1.000 23 0 1997 2019
Entrez Id: 2073
Gene Symbol: ERCC5
ERCC5
P28715 ERCC excision repair 5, endonuclease 238 0.499 0.731 2.7E-13 0.100 None 1.000 18 1 1993 2015
Entrez Id: 7376
Gene Symbol: NR1H2
NR1H2
P55055 nuclear receptor subfamily 1 group H member 2 Nuclear receptor 134 0.533 0.769 0.38 0.100 None 1.000 11 0 2000 2018
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.100 None 0.909 11 2 2003 2020
Entrez Id: 404672
Gene Symbol: GTF2H5
GTF2H5
Q6ZYL4 general transcription factor IIH subunit 5 152 0.556 0.769 4.5E-02 0.100 None 1.000 11 0 2000 2019
Entrez Id: 2967
Gene Symbol: GTF2H3
GTF2H3
Q13889 general transcription factor IIH subunit 3 Nucleic acid binding 41 0.656 0.615 3.0E-08 0.100 None 1.000 10 0 1993 2019
Entrez Id: 2966
Gene Symbol: GTF2H2
GTF2H2
Q13888 general transcription factor IIH subunit 2 Transcription factor 46 0.650 0.577 1.6E-02 0.100 None 1.000 10 0 1993 2019