|
| Entrez Id: |
351 |
| Gene Symbol: |
APP |
APP
|
P05067
|
amyloid beta precursor protein
|
Enzyme modulator
|
485
|
0.422 |
0.846 |
4.7E-02 |
0.400 |
None
|
0.988 |
86
|
5
|
1999 |
2020 |
|
| Entrez Id: |
348 |
| Gene Symbol: |
APOE |
APOE
|
P02649
|
apolipoprotein E
|
|
1049
|
0.338 |
0.962 |
1.9E-03 |
0.400 |
None
|
0.977 |
43
|
1
|
1996 |
2019 |
|
| Entrez Id: |
627 |
| Gene Symbol: |
BDNF |
BDNF
|
P23560
|
brain derived neurotrophic factor
|
Signaling
|
992
|
0.345 |
0.923 |
0.66 |
0.100 |
None
|
1.000 |
36
|
2
|
2006 |
2020 |
|
| Entrez Id: |
4137 |
| Gene Symbol: |
MAPT |
MAPT
|
P10636
|
microtubule associated protein tau
|
|
469
|
0.446 |
0.923 |
6.0E-03 |
0.400 |
None
|
1.000 |
18
|
3
|
2005 |
2019 |
|
| Entrez Id: |
2332 |
| Gene Symbol: |
FMR1 |
FMR1
|
Q06787
|
FMRP translational regulator 1
|
Nucleic acid binding
|
346
|
0.473 |
0.769 |
0.65 |
0.400 |
None
|
1.000 |
14
|
0
|
2003 |
2019 |
|
| Entrez Id: |
43 |
| Gene Symbol: |
ACHE |
ACHE
|
P22303
|
acetylcholinesterase (Cartwright blood group)
|
Enzyme
|
418
|
0.445 |
0.885 |
1.00 |
0.100 |
None
|
1.000 |
12
|
0
|
2010 |
2019 |
|
| Entrez Id: |
1859 |
| Gene Symbol: |
DYRK1A |
DYRK1A
|
Q13627
|
dual specificity tyrosine phosphorylation regulated kinase 1A
|
Kinase
|
212
|
0.533 |
0.769 |
1.00 |
0.100 |
None
|
1.000 |
12
|
0
|
2001 |
2018 |
|
| Entrez Id: |
1312 |
| Gene Symbol: |
COMT |
COMT
|
P21964
|
catechol-O-methyltransferase
|
Enzyme
|
622
|
0.400 |
0.923 |
1.1E-06 |
0.400 |
None
|
0.818 |
11
|
0
|
2006 |
2018 |
|
| Entrez Id: |
5663 |
| Gene Symbol: |
PSEN1 |
PSEN1
|
P49768
|
presenilin 1
|
Enzyme
|
369
|
0.469 |
0.846 |
0.97 |
0.400 |
None
|
1.000 |
11
|
2
|
1999 |
2018 |
|
| Entrez Id: |
5816 |
| Gene Symbol: |
PVALB |
PVALB
|
P20472
|
parvalbumin
|
Calcium-binding protein
|
148
|
0.547 |
0.692 |
8.7E-02 |
0.090 |
None
|
1.000 |
9
|
0
|
2003 |
2019 |
|
| Entrez Id: |
1137 |
| Gene Symbol: |
CHRNA4 |
CHRNA4
|
P43681
|
cholinergic receptor nicotinic alpha 4 subunit
|
Ion channel
|
248
|
0.492 |
0.808 |
8.5E-05 |
0.090 |
None
|
1.000 |
9
|
0
|
2012 |
2019 |
|
| Entrez Id: |
23621 |
| Gene Symbol: |
BACE1 |
BACE1
|
P56817
|
beta-secretase 1
|
Enzyme
|
120
|
0.559 |
0.769 |
0.88 |
0.090 |
None
|
1.000 |
9
|
0
|
2010 |
2019 |
|
| Entrez Id: |
4780 |
| Gene Symbol: |
NFE2L2 |
NFE2L2
|
Q16236
|
nuclear factor, erythroid 2 like 2
|
Enzyme
|
823
|
0.357 |
0.885 |
3.6E-03 |
0.090 |
None
|
1.000 |
9
|
0
|
2017 |
2019 |
|
| Entrez Id: |
27185 |
| Gene Symbol: |
DISC1 |
DISC1
|
Q9NRI5
|
DISC1 scaffold protein
|
|
136
|
0.548 |
0.769 |
1.7E-06 |
0.090 |
None
|
1.000 |
9
|
0
|
2006 |
2019 |
|
| Entrez Id: |
5294 |
| Gene Symbol: |
PIK3CG |
PIK3CG
|
P48736
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
|
Kinase
|
1101
|
0.320 |
0.885 |
1.4E-06 |
0.080 |
None
|
1.000 |
8
|
0
|
2017 |
2019 |
|
| Entrez Id: |
5290 |
| Gene Symbol: |
PIK3CA |
PIK3CA
|
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1511
|
0.292 |
0.923 |
1.00 |
0.080 |
None
|
1.000 |
8
|
0
|
2017 |
2019 |
|
| Entrez Id: |
5291 |
| Gene Symbol: |
PIK3CB |
PIK3CB
|
P42338
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
|
Kinase
|
1083
|
0.322 |
0.885 |
1.00 |
0.080 |
None
|
1.000 |
8
|
0
|
2017 |
2019 |
|
| Entrez Id: |
23411 |
| Gene Symbol: |
SIRT1 |
SIRT1
|
Q96EB6
|
sirtuin 1
|
Epigenetic regulator
|
675
|
0.378 |
0.885 |
8.7E-02 |
0.080 |
None
|
1.000 |
8
|
0
|
2017 |
2019 |
|
| Entrez Id: |
5293 |
| Gene Symbol: |
PIK3CD |
PIK3CD
|
O00329
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
|
Kinase
|
1119
|
0.319 |
0.885 |
1.00 |
0.080 |
None
|
1.000 |
8
|
0
|
2017 |
2019 |
|
| Entrez Id: |
2551 |
| Gene Symbol: |
GABPA |
GABPA
|
Q06546
|
GA binding protein transcription factor subunit alpha
|
Transcription factor
|
632
|
0.379 |
0.885 |
1.00 |
0.070 |
None
|
1.000 |
7
|
0
|
2017 |
2019 |
|
| Entrez Id: |
2932 |
| Gene Symbol: |
GSK3B |
GSK3B
|
P49841
|
glycogen synthase kinase 3 beta
|
Kinase
|
393
|
0.430 |
0.846 |
0.96 |
0.360 |
None
|
1.000 |
7
|
0
|
2014 |
2019 |
|
| Entrez Id: |
6622 |
| Gene Symbol: |
SNCA |
SNCA
|
P37840
|
synuclein alpha
|
Transporter
|
449
|
0.427 |
0.885 |
0.88 |
0.070 |
None
|
1.000 |
7
|
2
|
2008 |
2018 |
|
| Entrez Id: |
590 |
| Gene Symbol: |
BCHE |
BCHE
|
P06276
|
butyrylcholinesterase
|
|
392
|
0.447 |
0.923 |
1.1E-13 |
0.340 |
None
|
1.000 |
6
|
0
|
2001 |
2019 |
|
| Entrez Id: |
2475 |
| Gene Symbol: |
MTOR |
MTOR
|
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
960
|
0.343 |
0.885 |
1.00 |
0.060 |
None
|
0.833 |
6
|
0
|
2014 |
2019 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
P42858
|
huntingtin
|
|
188
|
0.548 |
0.654 |
1.00 |
0.060 |
None
|
1.000 |
6
|
0
|
2009 |
2019 |