Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.500 None 0.969 3 0 1986 2019
Entrez Id: 2520
Gene Symbol: GAST
GAST 		P01350 gastrin 21 0.485 0.808 2.7E-03 0.340 None 1.000 1 0 1986 2007
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.400 None 0.971 6 0 1987 2018
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 67 0.425 0.846 0.72 0.360 None 1.000 6 0 1988 2008
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.600 None 0.949 7 0 1990 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 1.000 2 0 1991 2018
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		P01344 insulin like growth factor 2 59 0.390 0.885 4.4E-02 0.320 None 1.000 1 0 1991 2012
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.350 None 1.000 1 0 1992 2015
Entrez Id: 4953
Gene Symbol: ODC1
ODC1 		P11926 ornithine decarboxylase 1 Enzyme 16 0.510 0.731 0.17 0.310 None 1.000 1 0 1992 2003
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		P05362 intercellular adhesion molecule 1 57 0.364 0.962 3.5E-02 0.310 None 1.000 2 0 1993 2006
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 31 0.399 0.808 3.4E-05 0.400 None 0.947 1 0 1994 2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 71 0.413 0.846 0.13 0.320 None 1.000 1 0 1995 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.600 None 1.000 3 0 1996 2019
Entrez Id: 5020
Gene Symbol: OXT
OXT 		P01178 oxytocin/neurophysin I prepropeptide Signaling 110 0.615 0.423 0.71 0.300 None 1.000 1 0 1996 1996
Entrez Id: 581
Gene Symbol: BAX
BAX 		Q07812 BCL2 associated X, apoptosis regulator Signaling 51 0.417 0.885 0.32 0.370 None 1.000 1 0 1997 2007
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 130 0.303 0.885 1.00 0.400 None 1.000 9 0 1998 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.560 None 1.000 3 0 1998 2009
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.320 None 1.000 4 0 1999 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.400 None 0.950 1 0 1999 2019
Entrez Id: 4316
Gene Symbol: MMP7
MMP7 		P09237 matrix metallopeptidase 7 Enzyme 10 0.446 0.885 1.0E-09 0.330 None 1.000 1 0 1999 2008
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 167 0.288 0.962 0.47 0.310 None 1.000 1 0 2000 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.370 None 1.000 1 0 2001 2011
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2 		Q9Y2T1 axin 2 20 0.507 0.692 0.57 0.330 None 1.000 1 0 2001 2009
Entrez Id: 1045
Gene Symbol: CDX2
CDX2 		Q99626 caudal type homeobox 2 Transcription factor 5 0.458 0.769 0.53 0.360 None 1.000 1 0 2001 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.530 None 1.000 4 0 2002 2019