Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 67 0.390 0.808 0.49 0.800 strong 0.966 0 1 1993 2020
Entrez Id: 699
Gene Symbol: BUB1
BUB1
O43683 BUB1 mitotic checkpoint serine/threonine kinase Kinase 6 0.528 0.731 4.9E-09 0.700 None 1.000 0 4 2000 2018
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 Kinase 49 0.391 0.846 1.6E-05 0.660 None 1.000 0 8 2000 2018
Entrez Id: 2033
Gene Symbol: EP300
EP300
Q09472 E1A binding protein p300 40 0.459 0.846 1.00 0.640 None 1.000 0 4 1996 2017
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 Kinase 39 0.435 0.808 0.99 0.600 strong 1.000 0 5 1998 2019
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B
O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 22 0.502 0.808 7.0E-10 0.540 None 1.000 0 1 2002 2016
Entrez Id: 4163
Gene Symbol: MCC
MCC
P23508 MCC regulator of WNT signaling pathway 12 0.568 0.731 4.7E-16 0.500 None 0.929 0 4 1991 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 9 0.352 0.962 0.500 None 0.975 0 3 1994 2020
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase Enzyme 19 0.521 0.769 1.3E-18 0.500 strong 0.947 0 9 2002 2019
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 31 0.484 0.808 4.5E-27 0.500 strong 0.967 0 1 1998 2020
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
Q9Y2T1 axin 2 20 0.507 0.692 0.57 0.500 None 0.905 0 3 2001 2019
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 67 0.420 0.885 0.68 0.480 None 1.000 0 1 2005 2019
Entrez Id: 10395
Gene Symbol: DLC1
DLC1
Q96QB1 DLC1 Rho GTPase activating protein 11 0.529 0.731 1.00 0.450 None 1.000 0 1 2013 2019
Entrez Id: 4035
Gene Symbol: LRP1
LRP1
Q07954 LDL receptor related protein 1 15 0.482 0.769 1.00 0.420 None 1.000 0 4 2015 2019
Entrez Id: 8029
Gene Symbol: CUBN
CUBN
O60494 cubilin 9 0.587 0.769 4.6E-42 0.410 None 1.000 0 2 2015 2019
Entrez Id: 3915
Gene Symbol: LAMC1
LAMC1
P11047 laminin subunit gamma 1 Enzyme modulator 6 0.628 0.654 1.00 0.410 None 1.000 0 4 2013 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.400 None 0.953 0 0 1997 2019
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 Transcription factor 15 0.456 0.808 1.00 0.400 None 0.963 0 0 1996 2019
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 23 0.421 0.923 6.3E-09 0.400 None 0.826 0 1 2000 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.400 strong 0.964 0 0 2000 2019
Entrez Id: 201163
Gene Symbol: FLCN
FLCN
Q8NFG4 folliculin 30 0.537 0.885 0.79 0.400 None 0 4
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 44 0.365 0.962 1.4E-03 0.400 None 1.000 0 1 1995 2019
Entrez Id: 4519
Gene Symbol: CYTB
CYTB
P00156 cytochrome b 4 0.529 0.808 0.400 None 0 2
Entrez Id: 4539
Gene Symbol: ND4L
ND4L
P03901 NADH dehydrogenase, subunit 4L (complex I) Enzyme 2 0.805 0.308 0.400 None 0 1
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
P35900 keratin 20 12 0.388 0.846 9.1E-11 0.400 None 0.923 0 0 1996 2019