Source: UNIPROT ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 4 0.399 0.808 3.4E-05 0.800 strong 0.973 11 14 1993 2020
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 4 0.406 0.808 0.90 0.800 strong 0.971 4 9 1993 2020
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 9 0.390 0.808 0.49 0.800 strong 0.966 0 1 1993 2020
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 4 0.373 0.962 1.00 0.800 strong 0.972 0 2 1990 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 10 0.319 0.846 1.00 0.700 None 0.976 4 5 2002 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 10 0.292 0.923 1.00 0.700 None 0.985 2 8 2002 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 7 0.303 0.885 1.00 0.700 None 0.983 1 1 1997 2020
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2 		Q9NQB0 transcription factor 7 like 2 1 0.485 0.846 1.00 0.700 None 0.925 0 0 1999 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		P84022 SMAD family member 3 Transcription factor 2 0.415 0.923 0.80 0.700 None 0.941 0 0 1998 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 5 0.401 0.808 1.00 0.700 strong 0.981 0 3 1996 2020
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 2 0.333 0.923 0.84 0.700 None 1.000 0 2 1992 2019
Entrez Id: 699
Gene Symbol: BUB1
BUB1 		O43683 BUB1 mitotic checkpoint serine/threonine kinase Kinase 2 0.528 0.731 4.9E-09 0.700 None 1.000 0 3 2000 2018
Entrez Id: 1630
Gene Symbol: DCC
DCC 		P43146 DCC netrin 1 receptor 4 0.471 0.808 0.99 0.700 None 0.946 0 1 1990 2019
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3 		P22607 fibroblast growth factor receptor 3 Kinase 17 0.391 0.846 1.6E-05 0.660 None 1.000 0 1 2000 2018
Entrez Id: 688
Gene Symbol: KLF5
KLF5 		Q13887 Kruppel like factor 5 Nucleic acid binding 1 0.534 0.769 0.82 0.640 None 1.000 0 0 2011 2019
Entrez Id: 2033
Gene Symbol: EP300
EP300 		Q09472 E1A binding protein p300 3 0.459 0.846 1.00 0.640 None 1.000 0 1 1996 2017
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		P52701 mutS homolog 6 Nucleic acid binding 5 0.462 0.731 3.7E-05 0.600 strong 0.974 12 32 1988 2020
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3 		P17936 insulin like growth factor binding protein 3 Enzyme modulator 1 0.439 0.808 0.91 0.600 None 0.815 0 1 2004 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 8 0.320 0.923 7.9E-04 0.600 None 0.963 0 4 1990 2020
Entrez Id: 3791
Gene Symbol: KDR
KDR 		P35968 kinase insert domain receptor Kinase 4 0.378 0.885 1.00 0.600 None 0.964 0 0 2002 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 12 0.435 0.808 0.99 0.600 strong 1.000 0 5 1998 2019
Entrez Id: 5979
Gene Symbol: RET
RET 		P07949 ret proto-oncogene Kinase 10 0.392 0.885 1.00 0.600 None 1.000 0 0 2008 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 1 0.344 0.885 1.3E-05 0.600 None 0.960 0 0 1990 2020
Entrez Id: 10135
Gene Symbol: NAMPT
NAMPT 		P43490 nicotinamide phosphoribosyltransferase Signaling 1 0.502 0.808 0.98 0.570 None 1.000 0 0 2013 2019
Entrez Id: 28234
Gene Symbol: SLCO1B3
SLCO1B3 		Q9NPD5 solute carrier organic anion transporter family member 1B3 Transporter 1 0.592 0.769 5.3E-24 0.550 None 1.000 0 1 2008 2020